NDLI: AIDS: an International Perspective

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AIDS: an International Perspective

Content Provider	Scilit
Author	Piot, Peter Plummer, Francis A. Mhalu, Fred S. Lamboray, Jean-Louis Chin, James Mann, Jonathan M.
Copyright Year	1988
Description	A very unusual molecular mechanism is involved in generating the preimmune repertoire in the chicken bursa of Fabricius. A unique rearranged V gene is diversified through a program of segmental gene conversion with a pool of noncoding pseudogenes being used as donors. A specifically committed progenitor that originates in the embryonic bursa is responsible for long-term maintenance of the B cell population. Both these properties and the characteristics of the peripheral B cell compartment are discussed in terms of the evolution of the T and B immune systems.
Related Links	http://doc.rero.ch/record/291696/files/S0376892900011577.pdf http://www.sciencemag.org/content/238/4830/1094.full.pdf
Ending Page	579
Page Count	7
Starting Page	573
ISSN	00368075
e-ISSN	10959203
DOI	10.1126/science.3277271
Journal	Science
Issue Number	4840
Volume Number	239
Language	English
Publisher	American Association for the Advancement of Science (AAAS)
Publisher Date	1988-02-05
Access Restriction	Open
Subject Keyword	Journal: Science Science Education Developing Country Developing Countries Drug Abuse Developed Countries Public Health Health Education Comparative Studies Research Methodology
Content Type	Text
Resource Type	Article
Subject	History and Philosophy of Science

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