NDLI: Fabrication of Microstructures Embedding Controllable Particles inside Dielectrophoretic Microfluidic Devices

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Fabrication of Microstructures Embedding Controllable Particles inside Dielectrophoretic Microfluidic Devices

Content Provider	SAGE Publishing
Author	Yue, Tao Nakajima, Masahiro Tajima, Hirotaka Fukuda, Toshio
Copyright Year	2013
Abstract	This paper presents a method of particle manipulation by dielectrophoresis (DEP) and immobilization using photo-crosslinkable resin inside microfluidic devices. High speed particle manipulation, including patterning and concentration control by DEP was demonstrated. Immovable and movable microstructures embedding particles were fabricated on-chip. Several microelectrodes were fabricated using Indium Tin Oxides (ITO) and Cr/Au. The two kinds of DEP responses of yeast cells (W303) and other particles were experimentally confirmed. Based on negative DEP phenomenon, cell traps generated by microelectrodes were demonstrated. Position control, transportation and patterning of cells were performed with cell traps. The on-chip fabrication of arbitrary shapes of microstructures based on Poly(ethylene glycol) diacrylate (PEGDA) was reported. With cell patterning by DEP and immobilization using on-chip fabrication, microstructures embedding line patterned cells were fabricated inside microfluidic channels. A novel microfluidic device was designed to separate patterning and fabrication areas and movable microstructures embedding concentration controllable particles were fabricated inside this device.
Related Links	https://journals.sagepub.com/doi/pdf/10.5772/55598?download=true
ISSN	17298806
Issue Number	2
Volume Number	10
Journal	International Journal of Advanced Robotic Systems (ARX)
e-ISSN	17298814
DOI	10.5772/55598
Language	English
Publisher	Sage Publications UK
Publisher Date	2017-05-15
Publisher Place	London
Access Restriction	Open
Rights Holder	© 2013 Yue et al.; licensee InTech.
Subject Keyword	On-Chip Fabrication Dielectrophoresis Microfluidic Devices Micromanipulation Microstructures
Content Type	Text
Resource Type	Article
Subject	Artificial Intelligence Computer Science Applications Software

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