NDLI: Pleiotropic Effects of Antiarrhythmic Agents: Dronedarone in the Treatment of Atrial Fibrillation

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Pleiotropic Effects of Antiarrhythmic Agents: Dronedarone in the Treatment of Atrial Fibrillation

Content Provider	SAGE Publishing
Author	Heijman, Jordi Heusch, Gerd Dobrev, Dobromir
Copyright Year	2013
Abstract	Atrial fibrillation remains the most common arrhythmia in clinical practice. Dronedarone is an antiarrhythmic drug for the maintenance of sinus rhythm in patients with atrial fibrillation. Dronedarone is an amiodarone derivative developed to reduce the number of extracardiovascular side effects. Dronedarone has undergone extensive experimental and clinical testing during the last decade. On the aggregate, these studies have highlighted a complex set of pleiotropic actions that may contribute to dronedarone's antiarrhythmic effects. In this review, we summarize the clinical studies that have evaluated dronedarone and provide an overview of dronedarone's electrophysiological and nonelectrophysiological pleiotropic actions.
Related Links	https://journals.sagepub.com/doi/pdf/10.4137/CMC.S8445?download=true
ISSN	11795468
Volume Number	7
Journal	Clinical Medicine Insights: Cardiology (CIC)
e-ISSN	11795468
DOI	10.4137/CMC.S8445
Language	English
Publisher	Sage Publications UK
Publisher Date	2013-08-11
Publisher Place	London
Access Restriction	Open
Rights Holder	© 2013 SAGE Publications.
Subject Keyword	antiarrhythmic drugs atrial fibrillation dronedarone pleiotropic effects
Content Type	Text
Resource Type	Article
Subject	Cardiology and Cardiovascular Medicine

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