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Clinical Performance of a Salivary Amylase Activity Monitor during Hemodialysis Treatment
| Content Provider | SAGE Publishing |
|---|---|
| Author | Shimazaki, Masaru Matsuki, Takayuki Yamauchi, Kazuaki Iwata, Michihiro Takahashi, Hiroshi Sakamoto, Kenichi Ohata, Junichi Nakamura, Yuichi Okazaki, Yusuke |
| Copyright Year | 2008 |
| Abstract | The hemodialysis procedure is thought to be a physical stressor in the majority of hemodialyzed patients. Previous studies suggest that elevated salivary amylase level may correlate with increased plasma norepinephrine level under psychological and physical stress conditions. In this study, we investigated biological stress reactivity during hemodialysis treatment using salivary amylase activity as a biomarker. Seven patients (male/female = 5/2, age:67.7+/–5.9 years) who had been receiving regular 4 h hemodialysis were recruited. Salivary amylase activity was measured using a portable analyzer every hour during the hemodialysis session. Salivary amylase activity was shown to be relatively stable and constant throughout hemodialysis, whereas there were significant changes in systolic blood pressure and pulse rate associated with blood volume reduction. Our results show that hemodialysis treatment per se dose not affect salivary amylase activity. |
| Related Links | https://journals.sagepub.com/doi/pdf/10.4137/BMI.S997?download=true |
| ISSN | 11772719 |
| Volume Number | 3 |
| Journal | Biomarker Insights (BMI) |
| e-ISSN | 11772719 |
| DOI | 10.4137/BMI.S997 |
| Language | English |
| Publisher | Sage Publications UK |
| Publisher Date | 2008-09-15 |
| Publisher Place | London |
| Access Restriction | Open |
| Rights Holder | © 2008 SAGE Publications. |
| Subject Keyword | stress biomarker hand-held monitor chronic renal failure salivary amylase activity hemodialysis |
| Content Type | Text |
| Resource Type | Article |
| Subject | Biochemistry (medical) Pharmacology Molecular Medicine |
