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Toxicological assessment of truebroc® glucoraphanin-rich broccoli seed extract
| Content Provider | SAGE Publishing |
|---|---|
| Author | Kruger, Claire Symonds, Jennifer Conze, Dietrich |
| Copyright Year | 2022 |
| Abstract | TrueBroc® Glucoraphanin-Rich Broccoli Seed Extract (TrueBroc®), is a hot water extract of Brassica oleracea var. Italica Plenck (Brassicaceae) seeds. The broccoli seeds are non-genetically modified and are tested and selected for their specific glucosinolate content. TrueBroc® contains greater than 99% of the aliphatic glucosinolate glucoraphanin and its precursor glucoerucin in the glucosinolate fraction. A battery of toxicology assays was conducted on TrueBroc® which includes in vitro and in vivo genotoxicity studies, an acute oral toxicity study in rats, a subchronic toxicology study in rats. The result from the subchronic rat study establishes a NOAEL of 1500 mg/kg/day. |
| Related Links | https://journals.sagepub.com/doi/pdf/10.1177/23978473211068834?download=true |
| ISSN | 23978473 |
| Volume Number | 6 |
| Journal | Toxicology Research and Application (TOR) |
| e-ISSN | 23978473 |
| DOI | 10.1177/23978473211068834 |
| Language | English |
| Publisher | Sage Publications UK |
| Publisher Date | 2022-02-03 |
| Publisher Place | London |
| Access Restriction | Open |
| Rights Holder | © The Author(s) 2022 |
| Subject Keyword | broccoli seed genotoxicology Glucoraphanin Brassica toxicology subchronic |
| Content Type | Text |
| Resource Type | Article |