NDLI: Severe Multi-Organ Failure and Hypereosinophilia: When to Call It “Idiopathic”?

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Severe Multi-Organ Failure and Hypereosinophilia: When to Call It “Idiopathic”?

Content Provider	SAGE Publishing
Author	Radin, Massimo Bertero, Luca Roccatello, Dario Sciascia, Savino
Copyright Year	2018
Abstract	The hypereosinophilic syndrome is a rare disease characterized by the association between high absolute eosinophil count and eosinophil-mediated organ damage. We describe a case of a 70-year-old male with an absolute eosinophil count of 2130 cells/µL. Clinical symptoms and signs included the following: severe asthenia, axonal sensitive motor neuropathy, basal pleural effusion with signs of hypoventilation on chest radiography, and gastrointestinal symptoms such as severe diarrhea, weight loss (−10 kg in 6 months), abdominal pain, and vomiting. On physical examination he had an urticarial dermatitis on his back, abdomen, and lower limbs. An extensive instrumental and laboratory diagnostic workup was performed. When all causes of primary and secondary hypereosinophilic syndrome were excluded, treatment with solumedrol infusion and oral prednisone was started, with a rapid recover of clinical symptoms and normalization of laboratory parameters. A complete remission of the laboratory and clinical findings was achieved after 2 months and maintained over 1-year follow-up.
Related Links	https://journals.sagepub.com/doi/pdf/10.1177/2324709618758347?download=true
ISSN	23247096
Volume Number	6
Journal	Journal of Investigative Medicine High Impact Case Reports (HIC)
e-ISSN	23247096
DOI	10.1177/2324709618758347
Language	English
Publisher	Sage Publications CA
Publisher Date	2018-02-15
Publisher Place	Los Angeles
Access Restriction	Open
Rights Holder	© 2018 American Federation for Medical Research
Subject Keyword	idiopathic hypereosinophilic syndrome hypereosinophilia IHES
Content Type	Text
Resource Type	Article
Subject	Safety Research Safety, Risk, Reliability and Quality Epidemiology

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