Loading...
Please wait, while we are loading the content...
Similar Documents
Frequency, Timing, and Prediction of Major Bleeding Complications From Percutaneous Renal Biopsy
| Content Provider | SAGE Publishing |
|---|---|
| Author | Schorr, Melissa Roshanov, Pavel S. Weir, Matthew A. House, Andrew A. |
| Copyright Year | 2020 |
| Abstract | Background and Objectives:The risk and timing of bleeding events following ultrasound-guided percutaneous renal biopsy are not clearly defined.Design setting, participants, and measurements:We performed a retrospective study of 617 consecutive adult patients who underwent kidney biopsy between 2012 and 2017 at a tertiary academic hospital in London, Canada. We assessed frequency and timing of minor (not requiring intervention) and major (requiring blood transfusion, surgery, or embolization) bleeds and developed a personalized risk calculator for these.Results:Bleeding occurred in 79 patients (12.8%; 95% confidence interval [CI]: 10.4%-15.7%). Minor bleeding occurred in 67 patients (10.9%; 95% CI: 8.6%-13.6%). Major bleeding occurred in 12 patients (1.9%; 95% CI: 1.1%-3.4%); 2 required embolization or surgery (0.3%; 95% CI: 0.09%-1.2%) and 10 required blood transfusion (1.6%; 95% CI: 0.9%-3.0%). Seventy-three of 79 events were identified immediately on post-procedure ultrasound (92.4% of cases; 95% CI: 84.4%-96.5%). Four of 617 patients experienced a minor event not detected immediately (0.6%; 95% CI: 0.3%-1.7%). Two patients (0.3%; 95% CI: 0.09%-1.2%) suffered a major complication that was not recognized immediately; both required blood transfusions only. There were no deaths or nephrectomies. A risk calculator using age, body mass index, platelet count, hemoglobin concentration, size of the target kidney, and whether the kidney is native, or an allograft predicted minor (C-statistic, 0.70) and major bleeding (C-statistic, 0.83).Conclusions:This retrospective study of 617 patients who had percutaneous ultrasound-guided renal biopsies supports the safety of short post-biopsy monitoring for most patients. A risk calculator can further personalize estimates of complication risk (http://perioperativerisk.com/kbrc). |
| Related Links | https://journals.sagepub.com/doi/pdf/10.1177/2054358120923527?download=true |
| ISSN | 20543581 |
| Volume Number | 7 |
| Journal | Canadian Journal of Kidney Health and Disease (CJK) |
| e-ISSN | 20543581 |
| DOI | 10.1177/2054358120923527 |
| Language | English |
| Publisher | Sage Publications CA |
| Publisher Date | 2020-05-25 |
| Publisher Place | Los Angeles |
| Access Restriction | Open |
| Rights Holder | © The Author(s) 2020 |
| Subject Keyword | bleeding risk prediction transplant kidney native kidney percutaneous renal biopsy timing complications |
| Content Type | Text |
| Resource Type | Article |
| Subject | Nephrology |
