NDLI: In vivo imaging techniques for bone tissue engineering

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In vivo imaging techniques for bone tissue engineering

Content Provider	SAGE Publishing
Author	Fragogeorgi, Eirini A. Rouchota, Maritina Georgiou, Maria Velez, Marisela Bouziotis, Penelope Loudos, George
Copyright Year	2019
Abstract	Bone is a dynamic tissue that constantly undergoes modeling and remodeling. Bone tissue engineering relying on the development of novel implant scaffolds for the treatment of pre-clinical bone defects has been extensively evaluated by histological techniques. The study of bone remodeling, that takes place over several weeks, is limited by the requirement of a large number of animals and time-consuming and labor-intensive procedures. X-ray-based imaging methods that can non-invasively detect the newly formed bone tissue have therefore been extensively applied in pre-clinical research and in clinical practice. The use of other imaging techniques at a pre-clinical level that act as supportive tools is convenient. This review mainly focuses on nuclear imaging methods (single photon emission computed tomography and positron emission tomography), either alone or used in combination with computed tomography. It addresses their application to small animal models with bone defects, both untreated and filled with substitute materials, to boost the knowledge on bone regenerative processes.
Related Links	https://journals.sagepub.com/doi/pdf/10.1177/2041731419854586?download=true
ISSN	20417314
Volume Number	10
Journal	Journal of Tissue Engineering (TEJ)
e-ISSN	20417314
DOI	10.1177/2041731419854586
Language	English
Publisher	Sage Publications UK
Publisher Date	2019-06-21
Publisher Place	London
Access Restriction	Open
Rights Holder	© The Author(s) 2019
Subject Keyword	Bone defects healing single photon emission computed tomography/positron emission tomography–computed tomography imaging substitute materials
Content Type	Text
Resource Type	Article
Subject	Medicine Biomaterials Biomedical Engineering

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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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