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Arylsulfonamides From the Roots and Rhizomes of Tupistra chinensis Baker
| Content Provider | SAGE Publishing |
|---|---|
| Author | Xu, Yue Liang, Xiaofei Li, Yuze Liang, Zhuofei Huang, Wenli Zhang, Huawei Jiang, Yi Cui, Jiucheng Song, Xiaomei |
| Copyright Year | 2020 |
| Abstract | One new arylsulfonamide (1) and a novel natural product (2) were isolated from the roots and rhizomes of Tupistra chinensis Baker. Their structures were characterized by physicochemical properties and spectroscopic methods, as 2-[2-([1,1′-biphenyl]-4-ylsulfonylamino)-benzoylamino]-benzoic acid methyl ester (1), 2-[([1,1′-biphenyl]-4-ylsulfonyl)amino]-benzoic acid (2), respectively. Additionally, the cytotoxic activity of 1-2 was evaluated on human HCT116, HT29, A549, and H1299 tumor cell lines in vitro, respectively. Whereas, the result showed that these compounds displayed weak cytotoxicity in the human cancer cell lines. |
| Related Links | https://journals.sagepub.com/doi/pdf/10.1177/1934578X20921665?download=true |
| ISSN | 1934578X |
| Issue Number | 4 |
| Volume Number | 15 |
| Journal | Natural Product Communications (NPX) |
| e-ISSN | 15559475 |
| DOI | 10.1177/1934578X20921665 |
| Language | English |
| Publisher | Sage Publications CA |
| Publisher Date | 2020-04-24 |
| Publisher Place | Los Angeles |
| Access Restriction | Open |
| Rights Holder | © The Author(s) 2020 |
| Subject Keyword | Tupistra chinensis Baker Cytotoxicity Arylsulfonamide |
| Content Type | Text |
| Resource Type | Article |
| Subject | Plant Science Drug Discovery Pharmacology Complementary and Alternative Medicine |
