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Sensitivity of postnatal fasting plasma glucose in identifying impaired glucose tolerance in women with gestational diabetes – 25 Years’ data

Content Provider	SAGE Publishing
Author	Kapaya, Habiba May, Lucy Jacques, Richard Madhuvrata, Priya
Copyright Year	2017
Abstract	ObjectiveTo assess the uptake of postnatal oral glucose tolerance test and to determine the sensitivity of fasting postnatal blood sugar in predicting 2-h impaired glucose tolerance.MethodsRetrospective study of 1961 women diagnosed with gestational diabetes mellitus. All women were offered oral glucose tolerance test six weeks post-delivery.ResultsOf 1961 women, 1090 (56%) returned for postpartum oral glucose tolerance test. A fasting plasma glucose of ≥6.1 mmol/l identified only 76 of 167 women with impaired glucose tolerance detected by a 2-h oral glucose tolerance test (sensitivity of 45.5%; 95%CI: 38.1–53.1). We observed a normal fasting glucose but an impaired 2-h glucose tolerance in 91 out of 968 (9.4%) women. Asian ethnicity, admission on special care baby unit and antenatal insulin therapy strongly predicted 2-h impaired postnatal blood glucose levels (P < 0.05).ConclusionAlthough fasting plasma glucose is a convenient method, it lacks sensitivity in identifying women with impaired glucose tolerance postnatally.
Related Links	https://journals.sagepub.com/doi/pdf/10.1177/1753495X17702786?download=true
Starting Page	125
Ending Page	131
Page Count	7
ISSN	1753495X
Issue Number	3
Volume Number	10
Journal	Obstetric Medicine (OBM)
e-ISSN	17534968
DOI	10.1177/1753495X17702786
Language	English
Publisher	Sage Publications UK
Publisher Date	2017-05-12
Publisher Place	London
Access Restriction	Open
Rights Holder	© The Author(s) 2017
Subject Keyword	oral glucose tolerance test fasting plasma glucose pregnancy screening diagnosis impaired glucose tolerance Gestational diabetes
Content Type	Text
Resource Type	Article
Subject	Obstetrics and Gynecology

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Sensitivity of postnatal fasting plasma glucose in identifying impaired glucose tolerance in women with gestational diabetes – 25 Years’ data