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Derecruitment volume assessment derived from pressure–impedance curves with electrical impedance tomography in experimental acute lung injury
| Content Provider | SAGE Publishing |
|---|---|
| Author | Sun, Xiu-Mei Chen, Guang-Qiang Wang, Yu-Mei Zhou, Yi-Min Chen, Jing-Ran Cheng, Kun-Ming Yang, Yan-Lin Zhang, Lin-lin Li, Hong-Liang Zhou, Jian-Xin |
| Copyright Year | 2020 |
| Abstract | ObjectiveTo investigate the accuracy of derecruitment volume (VDER) assessed by pressure–impedance (P-I) curves derived from electrical impedance tomography (EIT).MethodsSix pigs with acute lung injury received decremental positive end-expiratory pressure (PEEP) from 15 to 0 in steps of 5 cmH2O. At the end of each PEEP level, the pressure–volume (P-V) curves were plotted using the low constant flow method and release maneuvers to calculate the VDER between the PEEP of setting levels and 0 cmH2O (VDER-PV). The VDER derived from P-I curves that were recorded simultaneously using EIT was the difference in impedance at the same pressure multiplied by the ratio of tidal volume and corresponding tidal impedance (VDER-PI). The regional P-I curves obtained by EIT were used to estimate VDER in the dependent and nondependent lung.ResultsThe global lung VDER-PV and VDER-PI showed close correlations (r = 0.948, P<0.001); the mean difference was 48 mL with limits of agreement of −133 to 229 mL. Lung derecruitment extended into the whole process of decremental PEEP levels but was unevenly distributed in different lung regions.ConclusionsP-I curves derived from EIT can assess VDER and provide a promising method to estimate regional lung derecruitment at the bedside. |
| Related Links | https://journals.sagepub.com/doi/pdf/10.1177/0300060520949037?download=true |
| ISSN | 03000605 |
| Issue Number | 8 |
| Volume Number | 48 |
| Journal | Journal of International Medical Research (IMR) |
| e-ISSN | 14732300 |
| DOI | 10.1177/0300060520949037 |
| Language | English |
| Publisher | Sage Publications UK |
| Publisher Date | 2020-08-20 |
| Publisher Place | London |
| Access Restriction | Open |
| Rights Holder | © The Author(s) 2020 |
| Subject Keyword | Acute lung injury lung volume positive end-expiratory pressure lung derecruitment electric impedance pressure-volume curve |
| Content Type | Text |
| Resource Type | Article |
| Subject | Biochemistry (medical) Cell Biology Biochemistry |
