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Prevalence of hypertension and circadian blood pressure variations in patients with obstructive sleep apnoea–hypopnoea syndrome
| Content Provider | SAGE Publishing |
|---|---|
| Author | Wang, Yan Li, Caili Feng, Liting Feng, Jing Cao, Jie Chen, Baoyuan |
| Copyright Year | 2014 |
| Abstract | ObjectiveTo investigate the prevalence of hypertension and circadian blood pressure (BP) variations in patients with obstructive sleep apnoea–hypopnoea syndrome (OSAHS).MethodsPatients referred to a sleep clinic underwent polysomnography with measurement of BP at four time points. They were classified into four groups (control, and mild, moderate or severe sleep apnoea) using the apnoea–hypopnoea index (AHI). Circadian variation was assessed using night-time to daytime mean BP (RN/D) and morning to evening mean BP (RM/E) ratios.ResultsHypertension was significantly more common in patients with OSAHS (50.5%) than in controls (30.4%). AHI was positively correlated with hypertension after controlling for related confounders. Mean BP values at all four time points rose with increasing AHI. The increase in night-time and morning values was more pronounced than the increase in daytime and evening values in patients with OSAHS, resulting in loss of the normal BP diurnal rhythm. The RN/D and RM/E ratios increased with increasing AHI. Daytime BP was significantly correlated with AHI and the lowest oxygen saturation value.ConclusionOSAHS was shown to be an independent risk factor for hypertension. It was also associated with loss of the normal BP diurnal rhythm. |
| Related Links | https://journals.sagepub.com/doi/pdf/10.1177/0300060513516756?download=true |
| Starting Page | 773 |
| Ending Page | 780 |
| Page Count | 8 |
| ISSN | 03000605 |
| Issue Number | 3 |
| Volume Number | 42 |
| Journal | Journal of International Medical Research (IMR) |
| e-ISSN | 14732300 |
| DOI | 10.1177/0300060513516756 |
| Language | English |
| Publisher | Sage Publications UK |
| Publisher Date | 2014-03-20 |
| Publisher Place | London |
| Access Restriction | Open |
| Rights Holder | © The Author(s) 2014 |
| Subject Keyword | Obstructive sleep apnoea–hypopnoea syndrome hypertension apnoea–hypopnoea index circadian variation blood pressure lowest oxygen saturation |
| Content Type | Text |
| Resource Type | Article |
| Subject | Biochemistry (medical) Cell Biology Biochemistry |
