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Eustachian Tube Dysfunction in Children with Adenoid Hypertrophy: The Effect of Intranasal Azelastine-Fluticasone Spray Treatment on Middle Ear Ventilation and Adenoid Tissue
| Content Provider | SAGE Publishing |
|---|---|
| Author | Bilgili, Ahmet Mert Durmaz, Hacı Ömer Dilber, Muhammet |
| Copyright Year | 2022 |
| Abstract | ObjectivesEustachian tube dysfunction (ETD) is frequent in children with adenoid hypertrophy (AH). Although the most common treatment of AH is surgical removal of adenoid tissue, numerous studies have reported the efficacy of intranasal steroids. The effects of the intranasal steroid and azelastine combination on AH and ETD have not been reported before. In this study, we tried to determine the effects of 3-month intranasal Azelastine-Fluticasone dipropionate combination (Aze-Flu) treatment in children with ETD and AH.Materials and Methods100 children who had open mouth sleep, snoring, and sleep apnea and were diagnosed with AH and ETD participated in this study. The mean age was 7.73 ± 2.37 (4–14 years). The rates of adenoid tissue hypertrophy and choanal occlusion were evaluated using a rigid pediatric nasal endoscope and reassessed after 3 months of Aze-Flu nasal spray treatment. The function of the Eustachian tube (ET) was evaluated before and after medical treatment using the Eustachian tube score, the Eustachian dysfunction test-7 (ETS-7) and tubomanometry (TMM).ResultsThe results were evaluated in 100 patients with AH and ETD. The adenoid tissue to choana rate was 82% before treatment and decreased to 37% after treatment. The ETS-7 test score was 6.36 before treatment and increased to 9.72 at the end of 3 months. Both the regression of the adenoid tissue and the improvement in the Eustachian function scores were statistically significant (p < 0.05).ConclusionsAH significantly increases the frequency of ETD. In this study, it was observed that Aze-Flu treatment was significantly effective in both regression of the adenoid tissue and Eustachian tube dysfunction. We believe that it can be applied as an initial therapy in children with AH and associated ETD. |
| Related Links | https://journals.sagepub.com/doi/pdf/10.1177/01455613221140281?download=true |
| Starting Page | 198 |
| Ending Page | 203 |
| Page Count | 6 |
| ISSN | 01455613 |
| Issue Number | 3 |
| Volume Number | 102 |
| Journal | Ear, Nose & Throat Journal (EAR) |
| e-ISSN | 19427522 |
| DOI | 10.1177/01455613221140281 |
| Language | English |
| Publisher | Sage Publications CA |
| Publisher Date | 2022-11-23 |
| Publisher Place | Los Angeles |
| Access Restriction | Open |
| Rights Holder | © The Author(s) 2022 |
| Subject Keyword | otitis media with effusion Eustachian tube dysfunction adenoid hypertrophy Eustachian tube score azelastine fluticasone tympanometry |
| Content Type | Text |
| Resource Type | Article |
| Subject | Otorhinolaryngology |
