NDLI: Size-controlled synthesis of dendrimer-stabilized silver nanoparticles for X-ray computed tomography imaging applications

Please wait, while we are loading the content...

Uniaxially ordered conjugated polymer film prepared by electrochemical polymerization in a nematic liquid crystal with rubbing orientation method showing redox-driven tunable dichroism

Selenium-containing block copolymers and their oxidation-responsive aggregates

Synthesis of silica-polymer hybrids by combination of RAFT polymerization and azide-alkyne cycloaddition ‘click’ reactions

Synthesis and characterization of polythiophenes with alkenyl substituents

Effect of solvents on polymerization of N-propargylamide monomer and secondary structure of polymer

Preparation of shell cross-linked nanoparticles via miniemulsion RAFT polymerization

Synthesis and fluorescence properties of hyperbranched poly(amidoamine)s with high density tertiary nitrogen

Miktoarm core-crosslinked star copolymers with biologically active moieties on peripheries

A facile method for the homogeneous synthesis of cyanoethyl cellulose in NaOH/urea aqueous solutions

Dual hydrophilic polymers based on (meth)acrylic acid and poly(ethylene glycol) – synthesis and water uptake behavior

Size-controlled synthesis of dendrimer-stabilized silver nanoparticles for X-ray computed tomography imaging applications

Highly selective bisphenol A—imprinted polymers prepared by atom transfer radical polymerization

Free radical polymerization of alkyl methacrylates with N,N-dimethylanilinium p-toluenesulfonate at above ambient temperature: a quasi-living system

Hydrophilization of poly(ether ether ketone) films by surface-initiated atom transfer radical polymerization

Back matter

Back cover

Polymer Chemistry Vol - 1 Issue - 9

Polymer Chemistry Vol - 1 Issue - 8

Polymer Chemistry Vol - 1 Issue - 7

Polymer Chemistry Vol - 1 Issue - 6

Polymer Chemistry Vol - 1 Issue - 5

Polymer Chemistry Vol - 1 Issue - 4

Polymer Chemistry Vol - 1 Issue - 3

Polymer Chemistry Vol - 1 Issue - 2

Size-controlled synthesis of dendrimer-stabilized silver nanoparticles for X-ray computed tomography imaging applications

Content Provider	Royal Society of Chemistry (RSC)
Author	Zhang, Guixiang Shi, Xiangyang Guo, Rui Cao, Xueyan Zhao, Jinglong Luo, Yu Liu, Hui Shen, Mingwu Wang, Han
Copyright Year	2010
Abstract	We report a facile size-controlled synthesis of dendrimer-stabilized silver nanoparticles (Ag DSNPs) for X-ray computed tomography (CT) imaging applications. Amine-terminated generation 5 poly(amidoamine) dendrimers were used as templates to complex Ag(I) ions for subsequent reductive formation of dendrimer-entrapped Ag nanoparticles. Following a one-step acetylation reaction to transform dendrimer terminal amine to acetyl groups, Ag DSNPs can be formed. The formed Ag DSNPs were characterized using 1H NMR, UV-Vis spectrometry, transmission electron microscopy, and ζ-potential measurements. We show that through the variation of the dendrimer/Ag salt molar ratio, the size of Ag DSNPs can be controlled at the range of 8.8–23.2 nm. The formed Ag DSNPs are stable not only in water, PBS buffer, and fetal bovine serum, but also at different pH conditions (pH 5–8) and temperatures (20–50 °C). X-Ray absorption coefficient measurements show that the attenuation of Ag DSNPs is size-dependent, and the Ag DSNPs with a diameter of 16.1 nm display an X-ray attenuation intensity close to that of a clinically used iodine-based contrast agent (Omnipaque) at the same molar concentration of the active element (Ag versus iodine). This suggests that Ag DSNPs with an appropriate size have a great potential to be used as a CT imaging contrast agent, although the atomic number of Ag is lower than that of iodine. Furthermore, CT scanning showed prolonged enhancement at the point of mice injected subcutaneously with Ag DSNPs, rendering them as a promising contrast agent in CT imaging applications.
Starting Page	1677
Ending Page	1683
Page Count	7
File Format	HTM / HTML PDF
ISSN	17599954
Volume Number	1
Issue Number	10
Journal	Polymer Chemistry
DOI	10.1039/c0py00218f
Language	English
Publisher	Royal Society of Chemistry
Access Restriction	Open
Subject Keyword	PBS Dendrimer Atomic number Iohexol Contrast medium Concentration Fetal bovine serum X-ray crystallography Transmission electron microscopy Attenuation coefficient Poly(amidoamine) Acetylation Nuclear magnetic resonance CT scan Iodine
Content Type	Text
Resource Type	Article
Subject	Organic Chemistry Biochemistry Bioengineering Biomedical Engineering Polymers and Plastics

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Facile hydrothermal synthesis of low generation dendrimer-stabilized gold nanoparticles for in vivo computed tomography imaging applications

Poly(iohexol) nanoparticles as contrast agents for in vivo X-ray computed tomography imaging.

Nanoparticulate X-ray CT contrast agents

Poly(amidoamine)-Dendrimer-Stabilized Pd(0) Nanoparticles as a Catalyst for the Suzuki Reaction

Divergent growth of poly(amidoamine) dendrimer-like branched polymers at the reducing end of cellulose nanocrystals

X-ray differential phase contrast and dark-field computed tomography and radiography with microbubbles as contrast agent

SiO2–poly(amidoamine) dendrimer inorganic/organic hybrids

Targeted Tumor Computed Tomography Imaging Using Low-Generation Dendrimer-Stabilized Gold Nanoparticles

Cationic Poly(amidoamine) Dendrimer Induces Lysosomal Apoptotic Pathway at Therapeutically Relevant Concentrations

Size-controlled synthesis of dendrimer-stabilized silver nanoparticles for X-ray computed tomography imaging applications

Similar Documents

Facile hydrothermal synthesis of low generation dendrimer-stabilized gold nanoparticles for in vivo computed tomography imaging applications

Poly(iohexol) nanoparticles as contrast agents for in vivo X-ray computed tomography imaging.

Nanoparticulate X-ray CT contrast agents

Poly(amidoamine)-Dendrimer-Stabilized Pd(0) Nanoparticles as a Catalyst for the Suzuki Reaction

Divergent growth of poly(amidoamine) dendrimer-like branched polymers at the reducing end of cellulose nanocrystals

X-ray differential phase contrast and dark-field computed tomography and radiography with microbubbles as contrast agent

SiO2–poly(amidoamine) dendrimer inorganic/organic hybrids

Targeted Tumor Computed Tomography Imaging Using Low-Generation Dendrimer-Stabilized Gold Nanoparticles

Cationic Poly(amidoamine) Dendrimer Induces Lysosomal Apoptotic Pathway at Therapeutically Relevant Concentrations

Size-controlled synthesis of dendrimer-stabilized silver nanoparticles for X-ray computed tomography imaging applications