NDLI: Tellurium: an element with great biological potency and potential

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Organic & Biomolecular Chemistry Vol - 8 Issue - 9

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Tellurium: an element with great biological potency and potential

Content Provider	Royal Society of Chemistry (RSC)
Author	Jacob, Claus Ba, Lalla Aicha Jamier, Vincent Döring, Mandy
Copyright Year	2010
Abstract	Tellurium has long appeared as a nearly ‘forgotten’ element in Biology, with most studies focusing on tellurite, tellurate and a handful of organic tellurides. During the last decade, several discoveries have fuelled a renewed interest in this element. Bioincorporation of telluromethionine provides a new approach to add heavy atoms to selected sites in proteins. Cadmium telluride (CdTe) nanoparticles are fluorescent and may be used as quantum dots in imaging and diagnosis. The antibiotic properties of tellurite, long known yet almost forgotten, have attracted renewed interest, especially since the biochemical mechanisms of tellurium cytotoxicity are beginning to emerge. The close chemical relationship between tellurium and sulfur also transcends into in vitro and in vivo situations and provides new impetus for the development of enzyme inhibitors and redox modulators, some of which may be of interest in the field of antibiotics and anticancer drug design.
Starting Page	4203
Ending Page	4216
Page Count	14
File Format	HTM / HTML PDF
ISSN	14770520
Volume Number	8
Issue Number	19
Journal	Organic & Biomolecular Chemistry
DOI	10.1039/c0Ob00086h
Language	English
Publisher	Royal Society of Chemistry
Access Restriction	Open
Subject Keyword	Cadmium telluride Tellurite Antibiotics Enzyme Redox Tellurate Cytotoxicity Drug design Sulfur Tellurium
Content Type	Text
Resource Type	Article
Subject	Organic Chemistry Biochemistry Physical and Theoretical Chemistry

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Tellurite and Tellurate Reduction by the Aerobic Anoxygenic Phototroph Erythromonas ursincola, Strain KR99 Is Carried out by a Novel Membrane Associated Enzyme

Fluorescent Coumarin Thiols Measure Biological Redox Couples

Geobacillus stearothermophilus V ubiE gene product is involved in the evolution of dimethyl telluride in Escherichia coli K-12 cultures amended with potassium tellurate but not with potassium tellurite

Following the Headspace Production of Dimethyl Telluride Produced by Pseudomonas Fluorescens Amended with Sodium Tellurate or Sodium Tellurite

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Design, Synthesis and Biological Evaluation of β-Ketosulfonamide Adenylation Inhibitors as Potential Antitubercular Agents

Studies on the Selective Syntheses of Sodium Ditelluride and Dialkyl Ditellurides.

Tellurium: an element with great biological potency and potential

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Tellurite and Tellurate Reduction by the Aerobic Anoxygenic Phototroph Erythromonas ursincola, Strain KR99 Is Carried out by a Novel Membrane Associated Enzyme

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Tellurium: an element with great biological potency and potential