NDLI: Accumulation of rare earth elements in human bone within the lifespan

Please wait, while we are loading the content...

Metal use in ribonucleotide reductase R2, di-iron, di-manganese and heterodinuclear—an intricate bioinorganic workaround to use different metals for the same reaction

Zinc finger proteins as templates for metal ion exchange and ligand reactivity. Chemical and biological consequences

Cupredoxins—A study of how proteins may evolve to use metals for bioenergetic processes

Titanocene anticancer complexes and their binding mode of action to human serum albumin: A computational study

Investigation of the selenium metabolism in cancer cell lines

Characterization of the recombinant copper chaperone (CCS) from the plant Glycine (G.) max.

Absolute quantification of transferrin in blood samples of harbour seals using HPLC-ICP-MS

Accumulation of rare earth elements in human bone within the lifespan

High density array screening to identify the genetic requirements for transition metal tolerance in Saccharomyces cerevisiae

Prion protein expression level alters regional copper, iron and zinc content in the mouse brain

Back cover

Metallomics Vol -2

Metallomics Vol -1

Accumulation of rare earth elements in human bone within the lifespan

Content Provider	Royal Society of Chemistry (RSC)
Author	Nosenko, Sergey Zaichick, Vladimir Zaichick, Sofia Karandashev, Vasilii
Copyright Year	2011
Abstract	For the first time, the contents of rare earth elements (REEs) in a rib bone of a healthy human were determined. The mean value of the contents of Ce, Dy, Er, Gd, La, Nd, Pr, Sm, Tb, and Yb (10 elements out of 17 total REEs), as well as the upper limit of means for Ho, Lu, Tm, and Y (4 elements) were measured in the rib bone tissue of 38 females and 42 males (15 to 55 years old) using inductively coupled plasma mass spectrometry (ICP-MS). We found age-related accumulation of REEs in the bone tissue of healthy individuals who lived in a non-industrial region. It was calculated that during a lifespan the content of REEs in a skeleton of non-industrial region residents may increase by one to two orders of magnitude. Using our results as indicative normal values and published data we estimated relative Gd accumulation in the bone tissue of patients according to magnetic resonance imaging with contrast agent and La accumulation in the bone tissue of patients receiving hemodialysis after treatment with lanthanum carbonate as a phosphate binder. It was shown that after such procedures contents of Gd and La in the bone tissue of patients are two to three orders of magnitude higher than normal levels. In our opinion, REEs incorporation may affect bone quality and health similar to other potentially toxic trace metals. The impact of elevated REEs content on bone physiology, biochemistry and morphology requires further investigation.
Starting Page	186
Ending Page	194
Page Count	9
File Format	HTM / HTML PDF
ISSN	17565901
Volume Number	3
Issue Number	2
Journal	Metallomics
DOI	10.1039/c0mt00069h
Language	English
Publisher	Royal Society of Chemistry
Access Restriction	Open
Subject Keyword	Magnetic resonance imaging Lanthanum carbonate Hemodialysis Phosphate binder Lu Contrast medium Biochemistry Bone Inductively coupled plasma mass spectrometry
Content Type	Text
Resource Type	Article
Subject	Chemistry Medicine Metals and Alloys Biochemistry Biomaterials Biophysics

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Diverse accumulation and distribution of nutrient elements in developing wheat grain studied by laser ablation inductively coupled plasma mass spectrometry imaging

Determination of trace impurity rare earth elements in high-purity rare earth element samples using high-resolution inductively coupled plasma mass spectrometry

Identification and characterization of gadolinium(iii) complexes in biological tissue extracts

Bioimaging of metals in brain tissue by laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) and metallomics

Analysis of Europium, Yttrium and Lanthanum Compounds by Atomic Emission Spectrometry with Inductively Coupled Plasma

Fast Determination of Yttrium and Rare Earth Elements in Seawater by Inductively Coupled Plasma-Mass Spectrometry after Online Flow Injection Pretreatment

Precise Determination of Rare Earth Elements in Geological Standard Rocks by Inductively Coupled Plasma Source Mass Spectrometry

Analysis of pure scandium, yttrium, and their oxides using methods of inductively coupled plasma atomic emission spectrometry and inductively coupled plasma mass spectrometry

Determination of rare earth elements in geological samples by inductively coupled plasma mass spectrometry

Accumulation of rare earth elements in human bone within the lifespan

Similar Documents

Diverse accumulation and distribution of nutrient elements in developing wheat grain studied by laser ablation inductively coupled plasma mass spectrometry imaging

Determination of trace impurity rare earth elements in high-purity rare earth element samples using high-resolution inductively coupled plasma mass spectrometry

Identification and characterization of gadolinium(iii) complexes in biological tissue extracts

Bioimaging of metals in brain tissue by laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) and metallomics

Analysis of Europium, Yttrium and Lanthanum Compounds by Atomic Emission Spectrometry with Inductively Coupled Plasma

Fast Determination of Yttrium and Rare Earth Elements in Seawater by Inductively Coupled Plasma-Mass Spectrometry after Online Flow Injection Pretreatment

Precise Determination of Rare Earth Elements in Geological Standard Rocks by Inductively Coupled Plasma Source Mass Spectrometry

Analysis of pure scandium, yttrium, and their oxides using methods of inductively coupled plasma atomic emission spectrometry and inductively coupled plasma mass spectrometry

Determination of rare earth elements in geological samples by inductively coupled plasma mass spectrometry

Accumulation of rare earth elements in human bone within the lifespan