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| Content Provider | Royal Society of Chemistry (RSC) |
|---|---|
| Author | Sahlstrøm, Stefan Kirkhus, Bente Salt, Louise Jane Vegarud, Gerd Elisabeth Aarak, Kristi Ekrann Bengtsson, Gunnar Bengt Rigby, Neil Marcus Mackie, Alan Robert |
| Copyright Year | 2013 |
| Abstract | We hypothesize that the rate of release of lipids from salmon muscle during in vitro digestion is altered by additional meal components. In vitro digestion of salmon was performed using a mixture of porcine gastrointestinal enzymes and bile salts. Broccoli and barley were also added to the digestion simulating a meal. The extent of lipolysis was determined by measuring the release of fatty acids (FAs) during sampling at the simulated gastric phase endpoint (60 minutes) and 20, 40, 60, 80, 110 and 140 minutes simulated small intestinal phase, using solid phase extraction and GC-FID. Adding barley resulted in a lower overall release of FA from salmon, whereas broccoli caused an initial delay followed by increased release from 80–140 min when lipid digestion of salmon alone plateaued. The impact of broccoli and barley on the release of peptides and digesta viscosity were also measured. The effect of different components in the meal shown by this in vitro study suggests that it would be possible to make dietary changes affecting the lipolysis, further triggering specific responses in the gastrointestinal tract. However, these observations need to be validated in vivo, and the mechanisms need to be further examined. |
| Starting Page | 1819 |
| Ending Page | 1826 |
| Page Count | 8 |
| File Format | HTM / HTML PDF |
| ISSN | 20426496 |
| Volume Number | 4 |
| Issue Number | 12 |
| Journal | Food & Function |
| DOI | 10.1039/c3fo60346f |
| Language | English |
| Publisher | Royal Society of Chemistry |
| Access Restriction | Open |
| Subject Keyword | Salmon Digestive enzyme Bile acid Barley Lipolysis Solid phase extraction Broccoli Lipid Viscosity Gastrointestinal tract |
| Content Type | Text |
| Resource Type | Article |
| Subject | Medicine Food Science |
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