NDLI: Induction of micronuclei by multi-walled carbon nanotubes interacting with humic acids in cultured human lymphocytes

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Inside front cover

Contents list

Research highlights: engineering nanomaterial-based technologies for environmental applications

NanoEHS – defining fundamental science needs: no easy feat when the simple itself is complex

Recent advances in halloysite nanotube derived composites for water treatment

Formation of supported lipid bilayers containing phase-segregated domains and their interaction with gold nanoparticles

Silica nanoparticle-generated ROS as a predictor of cellular toxicity: mechanistic insights and safety by design

Effects of dysprosium oxide nanoparticles on Escherichia coli

Induction of micronuclei by multi-walled carbon nanotubes interacting with humic acids in cultured human lymphocytes

Surface engineering superparamagnetic nanoparticles for aqueous applications: design and characterization of tailored organic bilayers

Extremely high arsenic removal capacity for mesoporous aluminium magnesium oxide composites

Graphene–carbon nanotube aerogel as an ultra-light, compressible and recyclable highly efficient absorbent for oil and dyes

Accumulation of zinc, copper, or cerium in carrot (Daucus carota) exposed to metal oxide nanoparticles and metal ions

Interaction between palladium-doped zerovalent iron nanoparticles and biofilm in granular porous media: characterization, transport and viability

Non-covalent functionalization of high-surface area nanomaterials: a new class of sorbent materials

Aggregation and interactions of chemical mechanical planarization nanoparticles with model biological membranes: role of phosphate adsorption

Influence of a polymer sunscreen additive on the transport and retention of titanium dioxide nanoparticles in water-saturated porous media

Nanoproducts – what is actually available to European consumers?

Complex organic corona formation on carbon nanotubes reduces microbial toxicity by suppressing reactive oxygen species production

Effects of crystallite size on the structure and magnetism of ferrihydrite

Effect of humic acid on the kinetics of silver nanoparticle sulfidation

Water-compatible surface molecularly imprinted polymers with synergy of bi-functional monomers for enhanced selective adsorption of bisphenol A from aqueous solution

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Environmental Science: Nano Vol -2

Environmental Science: Nano Vol -1

Induction of micronuclei by multi-walled carbon nanotubes interacting with humic acids in cultured human lymphocytes

Content Provider	Royal Society of Chemistry (RSC)
Author	Gournis, Dimitrios Kouloumpis, Antonios Vlastos, Dimitris Bletsa, Eleni Skoutelis, Charalambos G. Deligiannakis, Yiannis Vidali, Maria-Sophia
Copyright Year	2016
Abstract	Mixtures of multi-walled carbon nanotubes (MWCNTs) with natural humic acids (Leonardite humic acid, LHA) or humic acid-like polycondensates (HALP) were evaluated, for the first time, about their potential genotoxic and cytotoxic effects in cultured human lymphocytes. The genotoxic evaluation of the tested materials, either separately or in combination, for the detection of micronuclei (MN) in the cytoplasm of interphase cells, was performed using the cytokinesis block micronucleus (CBMN) assay. A comparative analysis of the genotoxicity and cytotoxicity reveals that in the tested concentrations, the [MWCNTs + LHA] mixture is more genotoxic and slightly more cytotoxic than the [MWCNTs + HALP] mixture. MN induction observed in human lymphocytes demonstrates that humic substances enhance the genotoxic effects of MWCNTs. In addition, the present data highlight a – so far unforeseen – potential genotoxic effect as the result of both clastogenic and aneugenic actions of the particular mixtures on human lymphocytes.
Starting Page	74
Ending Page	84
Page Count	11
File Format	HTM / HTML PDF
ISSN	20518153
Volume Number	3
Issue Number	1
Journal	Environmental Science: Nano
DOI	10.1039/c5en00138b
Language	English
Publisher	Royal Society of Chemistry
Access Restriction	Open
Subject Keyword	Carbon nanotube Humic acid Leonardite Acid Genotoxicity Cytotoxicity Micronucleus Cytoplasm Interphase Cytokinesis
Content Type	Text
Resource Type	Article
Subject	Environmental Science Materials Science

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Cytotoxicity and genotoxicity of multi-walled carbon nanotubes with human ocular cells

Genotoxicity induced by arsenic compounds in peripheral human lymphocytes analysed by cytokinesis-block micronucleus.

Cytotoxicity and genotoxicity of multi-walled carbon nanotubes with human ocular cells

Carbon nanotube ecotoxicity in amphibians: assessment of ultiwalled carbon nanotubes and comparison with double-walled carbon nanotubes

Multi-walled carbon nanotubes induce cytotoxicity, genotoxicity and apoptosis in normal human dermal fibroblast cells.

In vitro chromosomal aberrations induced by various shapes of multi-walled carbon nanotubes (MWCNTs)

The Dispersion State of Tangled Multi-Walled Carbon Nanotubes Affects Their Cytotoxicity

Genotoxicity and Cytotoxicity of Multi-wall Carbon Nanotubes in Cultured Chinese Hamster Lung Cells in Comparison with Chrysotile A Fibers

Genotoxicity induced by arsenic compounds in peripheral human lymphocytes analysed by cytokinesis-block micronucleus assay,”Mutagenesis (2007)

Induction of micronuclei by multi-walled carbon nanotubes interacting with humic acids in cultured human lymphocytes

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