NDLI: Preparation of a mixed-mode of hydrophobic/cation-exchange polymer monolith and its application to analysis of six antidepressants in human plasma

Please wait, while we are loading the content...

Simultaneous colorimetric determination of dopamine and ascorbic acid based on the surface plasmon resonance band of colloidal silver nanoparticles using artificial neural networks

A flow-injection chemiluminescence method for determination of cinchona alkaloids in pharmaceuticals and biological fluids

The application of ultrasound for the improvement of analytical procedures: Determination of boron

Using a portable device based on a screen-printed sensor modified with a molecularly imprinted polymer for the determination of the insecticide fenitrothion in forest samples

Modeling the retention behavior of analytes in RPLC with mixed solvent mobile phases using Jouyban-Acree and Abraham models

A homogeneous time-resolved fluoroimmunoassay (TR-FIA) using antibody mediated luminescence quenching

A simple kinetic spectrophotometric method for simultaneous determination of tetracyclines by use of chemometrics

8-Hydroxyquinoline-5-sulfonic acid as the modifier for the determination of trace elements in cereals by slurry sampling electrothermal vaporization ICP-MS

Sensitive assay for picogram levels of sudan I in chilli foodstuffs by flow injection chemiluminescence

Qualitative and quantitative analysis of retinol, retinyl esters, tocopherols and selected carotenoids out of various internal organs from different species by HPLC

Preparation of a mixed-mode of hydrophobic/cation-exchange polymer monolith and its application to analysis of six antidepressants in human plasma

Novel extraction method based on the dispersion of the extraction solvent for extraction of letrozole from biological fluids

Amperometric measurement of gaseous hydrogen sulfide via a Clark-type approach

An immobilized dehydrohalogenase based potentiometric biosensor for the detection of chlorinated pesticides

Automatic lane detection and separation in one dimensional gel images using continuous wavelet transform

In situ Raman and IR spectroscopic analysis of indigo dye

Introduction of fluorescence and chemiluminescence detection to capillary chromatography based on tube radial distribution of water–hydrophilic–hydrophobic organic mixture carrier solvents

Towards an improved qualitative and quantitative determination of glutathione peroxidase, selenoprotein P and selenoalbumin in human serum by HPLC coupled to ICP-MS

Back matter

Back cover

Analytical Methods Vol - 2 Issue - 8

Analytical Methods Vol - 2 Issue - 7

Analytical Methods Vol - 2 Issue - 6

Analytical Methods Vol - 2 Issue - 5

Analytical Methods Vol - 2 Issue - 4

Analytical Methods Vol - 2 Issue - 3

Analytical Methods Vol - 2 Issue - 2

Analytical Methods Vol -1

Preparation of a mixed-mode of hydrophobic/cation-exchange polymer monolith and its application to analysis of six antidepressants in human plasma

Content Provider	Royal Society of Chemistry (RSC)
Author	Feng, Yu-Qi Shi, Zhi-Guo Xu, Jin Lu, Yang Ma, Qiao
Copyright Year	2010
Abstract	A hydrophobic/cation-exchange polymer monolith was prepared via one-step thermally initiated polymerization of 2-acrylamido-2-methyl-1-propyl-sulfonic acid (AMPS), divinylbenzene (DVB) and ethylene glycol dimethacrylate (EDMA) in a capillary. The use of DVB and EDMA as binary crosslinking monomers help to increase the specific surface area and enhance hydrophobicity of the target monolith. The as-obtained monolith was characterized by diffuse reflectance infrared spectroscopy, scanning electron microscopy, nitrogen adsorption–desorption and mercury intrusion porosimetry. The results show that the monolith has favorable permeability and well mechanical strength. Furthermore, its specific surface area is up to 353 m2 g−1. The as-prepared monolith was used as a sorbent for polymer monolith microextraction (PMME), which was coupled to high performance liquid chromatographic-electrospray ionization-mass spectrometric (HPLC-ESI-MS) analysis in off-line mode for the determination of antidepressants in biological samples. The results show that the monolith with hydrophobic and strong cation-exchange functional groups exhibits high extraction efficiency towards the antidepressants. The limits of detections (S/N = 3) for the antidepressants in plasma samples were in the range of 0.06–0.39 ng mL−1 and the recoveries were from 73.2% to 110.8% (depending on the analytes), with relative standard deviations (RSDs) less than 9.8%.
Starting Page	1333
Ending Page	1340
Page Count	8
File Format	HTM / HTML PDF
ISSN	17599660
Volume Number	2
Issue Number	9
Journal	Analytical Methods
DOI	10.1039/c0ay00228c
Language	English
Publisher	Royal Society of Chemistry
Access Restriction	Open
Subject Keyword	Infrared spectroscopy Acid Divinylbenzene Porosimetry Monolith Advanced Mobile Phone System Permeation Polymerization Polymer Specific surface area Hydrophobe Nitrogen Scanning electron microscope Digital Video Broadcasting Blood plasma EDMA Adsorption Mercury-vapor lamp Ethylene glycol dimethacrylate Ion exchange
Content Type	Text
Resource Type	Article
Subject	Analytical Chemistry Engineering Chemical Engineering

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Fast preparation of a hydrophobic monolith by redox initiation and its application in the separation of small molecules

Preparation of sorbent based on porous monolith incorporated with graphene oxide nanosheets for stir cake sorptive extraction of strongly polar aromatic amines

A simple and efficient method for preparation of a strong cation exchange monolith and its application to separation of HSA

Mono- or narrow disperse poly(methacrylate-co-divinylbenzene) microspheres by precipitation polymerization

Synthesis, characterization and adsorption performance of molecularly imprinted nanoparticles for tripterine by precipitation polymerization

Nonswellable and swellable ethylene glycol dimethacrylate-acrylic acid copolymer microspheres

Interfacing monolith-based electrochromatography in microchips with inductively coupled plasma mass spectrometry for elemental speciation

Resin and carbon foam production by cationic step-growth polymerization of organic carbonates

Automated analysis of non-steroidal anti-inflammatory drugs in human plasma and water samples by in-tube solid-phase microextraction coupled to liquid chromatography-mass spectrometry based on a poly(4-vinylpyridine-co-ethylene dimethacrylate) monolith

Preparation of a mixed-mode of hydrophobic/cation-exchange polymer monolith and its application to analysis of six antidepressants in human plasma

Similar Documents

Fast preparation of a hydrophobic monolith by redox initiation and its application in the separation of small molecules

Preparation of sorbent based on porous monolith incorporated with graphene oxide nanosheets for stir cake sorptive extraction of strongly polar aromatic amines

A simple and efficient method for preparation of a strong cation exchange monolith and its application to separation of HSA

Mono- or narrow disperse poly(methacrylate-co-divinylbenzene) microspheres by precipitation polymerization

Synthesis, characterization and adsorption performance of molecularly imprinted nanoparticles for tripterine by precipitation polymerization

Nonswellable and swellable ethylene glycol dimethacrylate-acrylic acid copolymer microspheres

Interfacing monolith-based electrochromatography in microchips with inductively coupled plasma mass spectrometry for elemental speciation

Resin and carbon foam production by cationic step-growth polymerization of organic carbonates

Automated analysis of non-steroidal anti-inflammatory drugs in human plasma and water samples by in-tube solid-phase microextraction coupled to liquid chromatography-mass spectrometry based on a poly(4-vinylpyridine-co-ethylene dimethacrylate) monolith

Preparation of a mixed-mode of hydrophobic/cation-exchange polymer monolith and its application to analysis of six antidepressants in human plasma