NDLI: A voltammetric method for analyzing the apoptosis of K562 cells

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A voltammetric method for analyzing the apoptosis of K562 cells

Content Provider	Royal Society of Chemistry (RSC)
Author	Cheng, Kang Wang, Ru-Ji Luo, Guo-An Feng, Jun Wang, De-Bing
Copyright Year	1999
Abstract	A voltammetric method for analyzing the effectiveness of anti-tumor drugs was investigated. In this paper, we providea method to describe the effectiveness of Vp16 (4′-demethyl-epipodophylotoxin-β-D-ethylidone-pyranoglucoside) on K562 cells. The voltammetric responses of apoptotic K562 cells showed a tendency to decrease compared with those of the control group of K562 cells and this inclination began from a relatively early stage in the cell culture course. In the same process of apoptosis, a DNA ladder of K562 cells was observed by agarose gel electrophoresis. Therefore, the faradic difference of K562 cells in apoptosis and in the control group was a sign of apoptosis and may provide a valuable method for evaluating cell apoptosis at an early stage.
Starting Page	379
Ending Page	381
Page Count	3
File Format	PDF
ISSN	13597337
Volume Number	36
Issue Number	11-12
Journal	Analytical Communications
DOI	10.1039/a906844i
Language	English
Publisher	Royal Society of Chemistry
Access Restriction	Open
Subject Keyword	Cell culture Molecular-weight size marker K562 cells Gel electrophoresis Orbital inclination Apoptosis
Content Type	Text
Resource Type	Article
Subject	Analytical Chemistry

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