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Serological and molecular findings during SARS-CoV-2 infection: the first case study in Finland, January to February 2020
| Content Provider | PubMed Central |
|---|---|
| Author | Haveri, Anu Smura, Teemu Kuivanen, Suvi Österlund, Pamela Hepojoki, Jussi Ikonen, Niina Pitkäpaasi, Marjaana Blomqvist, Soile Rönkkö, Esa Kantele, Anu Strandin, Tomas Kallio-Kokko, Hannimari Mannonen, Laura Lappalainen, Maija Broas, Markku Jiang, Miao Siira, Lotta Salminen, Mika Puumalainen, Taneli Sane, Jussi Melin, Merit Vapalahti, Olli Savolainen-Kopra, Carita |
| Copyright Year | 2020 |
| Abstract | The first case of coronavirus disease (COVID-19) in Finland was confirmed on 29 January 2020. No secondary cases were detected. We describe the clinical picture and laboratory findings 3–23 days since the first symptoms. The SARS-CoV-2/Finland/1/2020 virus strain was isolated, the genome showing a single nucleotide substitution to the reference strain from Wuhan. Neutralising antibody response appeared within 9 days along with specific IgM and IgG response, targeting particularly nucleocapsid and spike proteins. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096774/pdf/eurosurv-25-11-4.pdf |
| ISSN | 15607917 |
| e-ISSN | 15607917 |
| e-ISSN | 1025496X |
| Issue Number | 11 |
| Journal | Eurosurveillance |
| PubMed Central reference number | PMC7096774 |
| Volume Number | 25 |
| DOI | 10.2807/1560-7917.ES.2020.25.11.2000266 |
| Language | English |
| Publisher | European Centre for Disease Prevention and Control (ECDC) |
| Publisher Date | 2020-03-19 |
| Access Restriction | Open |
| Subject Keyword | SARS-CoV-2 COVID-19 coronavirus antibodies humoral immunity whole-genome sequencing microneutralisation test immunofluorescence assay western blotting |
| Content Type | Text |
| Resource Type | Article |
| Subject | Virology Public Health, Environmental and Occupational Health Epidemiology |
