NDLI: Regulation of Fumonisin B1 Biosynthesis and Conidiation in Fusarium verticillioides by a Cyclin-Like (C-Type) Gene, FCC1 †

Content Provider	PubMed Central
Author	Shim, Won-bo Woloshuk, Charles P.
Copyright Year	2001
Abstract	Fumonisins are a group of mycotoxins produced in corn kernels by the plant-pathogenic fungus Fusarium verticillioides. A mutant of the fungus, FT536, carrying a disrupted gene named FCC1 (for Fusarium cyclin C1) resulting in altered fumonisin B1 biosynthesis was generated. FCC1 contains an open reading frame of 1,018 bp, with one intron, and encodes a putative 319-amino-acid polypeptide. This protein is similar to UME3 (also called SRB11 or SSN8), a cyclin C of Saccharomyces cerevisiae, and contains three conserved motifs: a cyclin box, a PEST-rich region, and a destruction box. Also similar to the case for C-type cyclins, FCC1 was constitutively expressed during growth. When strain FT536 was grown on corn kernels or on defined minimal medium at pH 6, conidiation was reduced and FUM5, the polyketide synthase gene involved in fumonisin B1 biosynthesis, was not expressed. However, when the mutant was grown on a defined minimal medium at pH 3, conidiation was restored, and the blocks in expression of FUM5 and fumonisin B1 production were suppressed. Our data suggest that FCC1 plays an important role in signal transduction regulating secondary metabolism (fumonisin biosynthesis) and fungal development (conidiation) in F. verticillioides.
Related Links	http://dx.doi.org/10.1128/aem.67.4.1607-1612.2001
Ending Page	1612
Page Count	6
Starting Page	1607
File Format	PDF
ISSN	00992240
e-ISSN	10985336
Journal	Applied and Environmental Microbiology
Issue Number	4
Volume Number	67
Language	English
Publisher	American Society for Microbiology
Publisher Date	2001-04-01
Access Restriction	Open
Rights Holder	American Society for Microbiology
Subject Keyword	Biotechnology Food Science Ecology Applied Microbiology and Biotechnology Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Ecology Food Science Applied Microbiology and Biotechnology Biotechnology

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Regulation of Fumonisin Biosynthesis in Fusarium verticillioides by a Zinc Binuclear Cluster-Type Gene, ZFR1 †

Production of fumonisin B1 by Fusarium moniliforme NRRL 13616 in submerged culture.

Incidence of Fusarium verticillioides and levels of fumonisin B1 and B2 in corn in Turkey

Influence of Kernel Age on Fumonisin B1 Production in Maize by Fusarium moniliforme

PAC1, a pH-Regulatory Gene from Fusarium verticillioides †

Inhibition of fengycins on the production of fumonisin $B_{1}$fromFusarium verticillioides

Effects of temperature and incubation period on production of fumonisin B1 by Fusarium moniliforme.

Thermostability of Fumonisin B1, a Mycotoxin from Fusarium moniliforme, in Corn

Fumonisin B1 production by Fusarium species other than F. moniliforme in section Liseola and by some related species.

Regulation of Fumonisin B1 Biosynthesis and Conidiation in Fusarium verticillioides by a Cyclin-Like (C-Type) Gene, FCC1 †

Similar Documents

Regulation of Fumonisin Biosynthesis in Fusarium verticillioides by a Zinc Binuclear Cluster-Type Gene, ZFR1 †

Production of fumonisin B1 by Fusarium moniliforme NRRL 13616 in submerged culture.

Incidence of Fusarium verticillioides and levels of fumonisin B1 and B2 in corn in Turkey

Influence of Kernel Age on Fumonisin B1 Production in Maize by Fusarium moniliforme

PAC1, a pH-Regulatory Gene from Fusarium verticillioides †

Inhibition of fengycins on the production of fumonisin $B_{1}$fromFusarium verticillioides

Effects of temperature and incubation period on production of fumonisin B1 by Fusarium moniliforme.

Thermostability of Fumonisin B1, a Mycotoxin from Fusarium moniliforme, in Corn

Fumonisin B1 production by Fusarium species other than F. moniliforme in section Liseola and by some related species.

Regulation of Fumonisin B1 Biosynthesis and Conidiation in Fusarium verticillioides by a Cyclin-Like (C-Type) Gene, FCC1 †