NDLI: Stearoyl-acyl-carrier-protein desaturase from higher plants is structurally unrelated to the animal and fungal homologs.

Please wait, while we are loading the content...

Year: 2016, Volume: 113

Year: 2015, Volume: 112

Year: 2014, Volume: 111

Year: 2013, Volume: 110

Year: 2012, Volume: 109

Year: 2011, Volume: 109

Year: 2011, Volume: 108

Year: 2010, Volume: 107

Year: 2009, Volume: 106

Year: 2009, Volume: 94

Year: 2008, Volume: 105

Year: 2007, Volume: 104

Year: 2006, Volume: 103

Year: 2005, Volume: 103

Year: 2005, Volume: 102

Year: 2004, Volume: 101

Year: 2003, Volume: 100

Year: 2002, Volume: 99

Year: 2001, Volume: 98

Year: 2000, Volume: 97

Year: 1999, Volume: 96

Year: 1998, Volume: 95

Year: 1997, Volume: 94

Year: 1996, Volume: 93

Year: 1995, Volume: 92

Year: 1994, Volume: 91

Year: 1993, Volume: 90

Year: 1992, Volume: 89

Year: 1991, Volume: 88

Year: 1991, Volume: 88, Issue: 24

Year: 1991, Volume: 88, Issue: 23

Year: 1991, Volume: 88, Issue: 22

Year: 1991, Volume: 88, Issue: 21

Year: 1991, Volume: 88, Issue: 20

Year: 1991, Volume: 88, Issue: 19

Year: 1991, Volume: 88, Issue: 18

Year: 1991, Volume: 88, Issue: 17

Year: 1991, Volume: 88, Issue: 16

Year: 1991, Volume: 88, Issue: 15

Year: 1991, Volume: 88, Issue: 14

Year: 1991, Volume: 88, Issue: 13

Year: 1991, Volume: 88, Issue: 12

Year: 1991, Volume: 88, Issue: 11

Year: 1991, Volume: 88, Issue: 10

Year: 1991, Volume: 88, Issue: 9

Year: 1991, Volume: 88, Issue: 8

Year: 1991, Volume: 88, Issue: 7

Year: 1991, Volume: 88, Issue: 6

Tyrosine phosphatase CD45 is required for T-cell antigen receptor and CD2-mediated activation of a protein tyrosine kinase and interleukin 2 production.

Biosynthesis of the thiazole moiety of thiamin (vitamin B1) in higher plant chloroplasts.

Design, synthesis, and functional expression of a gene for charybdotoxin, a peptide blocker of K+ channels.

Locations of the three primary binding sites for long-chain fatty acids on bovine serum albumin.

Incorporation of 12-methoxydodecanoate into the human immunodeficiency virus 1 gag polyprotein precursor inhibits its proteolytic processing and virus production in a chronically infected human lymphoid cell line.

Molecular evolution of alcohol dehydrogenase 1 in members of the grass family.

FVB/N: an inbred mouse strain preferable for transgenic analyses.

Overexpression of beta 2-microglobulin in transgenic mouse islet beta cells results in defective insulin secretion.

Unexpected, spontaneous conversion of a family of rats, from low-leukemic to high-leukemic inbred line.

Cocaine-induced reduction of brain neuropeptide Y synthesis dependent on medial prefrontal cortex.

A novel cytoarchitectonic area induced experimentally within the primate visual cortex.

Corticosterone levels determine individual vulnerability to amphetamine self-administration.

Dendritic location of neural BC1 RNA.

Ultrastructural localization of beta-amyloid, tau, and ubiquitin epitopes in extracellular neurofibrillary tangles.

Determination of pathways of glycogen synthesis and the dilution of the three-carbon pool with [U-13C]glucose.

A second maternally expressed Drosophila gene encodes a putative RNA helicase of the "DEAD box" family.

Stable integrative transformation of Trypanosoma brucei that occurs exclusively by homologous recombination.

Isolation and characterization of a cDNA clone encoding an alternative oxidase protein of Sauromatum guttatum (Schott).

Diacylglycerols induce both ion pumping in patch-clamped guard-cell protoplasts and opening of intact stomata.

Adrenergic regulation of the skeletal alpha-actin gene promoter during myocardial cell hypertrophy.

Laventiana annectens, new genus and species: fossil evidence for the origins of callitrichine New World monkeys.

Comparison of constitutive and inducible transcriptional enhancement mediated by kappa B-related sequences: modulation of activity in B cells by human T-cell leukemia virus type I tax gene.

Founder effect of a prevalent phenylketonuria mutation in the Oriental population.

Receptor-stimulated death pathway is opened by antigen in mature T cells.

Protein kinase C mediates x-ray inducibility of nuclear signal transducers EGR1 and JUN.

Different mRNAs code for dopa decarboxylase in tissues of neuronal and nonneuronal origin.

Development and mechanism of a specific supersensitivity to nitrovasodilators after inhibition of vascular nitric oxide synthesis in vivo.

Reconstitution of high-affinity opioid agonist binding in brain membranes.

Einstein's equations with an embedding-dependent energy-momentum tensor for the compactified Minkowski time space and their relationship to the conformal action of SO(4,4) on S3 x S3.

Stable integration and expression in mouse cells of yeast artificial chromosomes harboring human genes.

A retinoic acid response element is part of a pleiotropic domain in the phosphoenolpyruvate carboxykinase gene.

Binding of soluble CD4 proteins to human immunodeficiency virus type 1 and infected cells induces release of envelope glycoprotein gp120.

Genetic relationship between acylpeptide hydrolase and acylase, two hydrolytic enzymes with similar binding but different catalytic specificities.

Fibroblast growth factor-mediated proliferation of central nervous system precursors depends on endogenous production of insulin-like growth factor I.

Identification of a T-cell-specific enhancer at the locus encoding T-cell antigen receptor gamma chain.

X-ray diffraction study of the binding of the antisickling agent 12C79 to human hemoglobin.

The transcriptional regulator LevR of Bacillus subtilis has domains homologous to both sigma 54- and phosphotransferase system-dependent regulators.

Transforming function of proto-ras genes depends on heterologous promoters and is enhanced by specific point mutations.

Dual site model for the organogenic activity of angiogenin.

An angiogenin-binding protein from endothelial cells.

Inositol trisphosphate receptor: phosphorylation by protein kinase C and calcium calmodulin-dependent protein kinases in reconstituted lipid vesicles.

Identification and purification to near homogeneity of the vitamin K-dependent carboxylase.

Differential scanning calorimetry of plant cell walls.

Regulation of luteinizing hormone-releasing hormone receptor binding by heterologous and autologous receptor-stimulated tyrosine phosphorylation.

A soluble factor induced by an extract from Pinus parviflora Sieb et Zucc can inhibit the replication of human immunodeficiency virus in vitro.

Transport of lipoprotein lipase across endothelial cells.

Transcription is associated with Z-DNA formation in metabolically active permeabilized mammalian cell nuclei.

An enhancer variant of Moloney murine leukemia virus defective in leukemogenesis does not generate detectable mink cell focus-inducing virus in vivo.

Identification and characterization of nonsedimentable lipid-protein microvesicles.

The pituitary gland is required for protection against lethal effects of Salmonella typhimurium.

Mechanisms associated with the generation of biologically active human immunodeficiency virus type 1 particles from defective proviruses.

Protection against lethal Sendai virus infection by in vivo priming of virus-specific cytotoxic T lymphocytes with a free synthetic peptide.

Straight and paired helical filaments in Alzheimer disease have a common structural unit.

A pioneering growth cone in the embryonic zebrafish brain.

Approximate entropy as a measure of system complexity.

Ultrasensitive fluorometric detection of carbohydrates as derivatives in mixtures separated by capillary electrophoresis.

Curved DNA without A-A: experimental estimation of all 16 DNA wedge angles.

Methylation patterns of testis-specific genes.

Bergmann's rule near the equator: latitudinal clines in body size of an Andean passerine bird.

Shaping and reshaping of salmonid genomes by amplification of tRNA-derived retroposons during evolution.

The second amino acid of alfalfa mosaic virus coat protein is critical for coat protein-mediated protection.

Rapid identification of markers linked to a Pseudomonas resistance gene in tomato by using random primers and near-isogenic lines.

The c-fms gene complements the mitogenic defect in mast cells derived from mutant W mice but not mi (microphthalmia) mice.

Invariant chain promotes egress of poorly expressed, haplotype-mismatched class II major histocompatibility complex A alpha A beta dimers from the endoplasmic reticulum/cis-Golgi compartment.

Normal and leukemic hematopoietic cells manifest differential sensitivity to inhibitory effects of c-myb antisense oligodeoxynucleotides: an in vitro study relevant to bone marrow purging.

Norepinephrine and isoproterenol increase the phosphorylation of synapsin I and synapsin II in dentate slices of young but not aged Fisher 344 rats.

Odorant-sensitive adenylate cyclase: rapid, potent activation and desensitization in primary olfactory neuronal cultures.

Sodium pump isozymes are differentially expressed in electrically dissimilar regions of colonic circular smooth muscle.

Expression of the human apolipoprotein E gene suppresses steroidogenesis in mouse Y1 adrenal cells.

Splice junctions follow a 205-base ladder.

Aspirin inhibits interleukin 1-induced prostaglandin H synthase expression in cultured endothelial cells.

Protein dynamics in the bacteriorhodopsin photocycle: submillisecond Fourier transform infrared spectra of the L, M, and N photointermediates.

Assimilate movement dictates remote sites of wound-induced gene expression in poplar leaves.

Adhesion protein GMP140 inhibits superoxide anion release by human neutrophils.

Error bounds for the fundamental and secondary theorems of natural selection.

Protamine transcript sharing among postmeiotic spermatids.

Identity of a second type of allatostatin from cockroach brains: an octadecapeptide amide with a tyrosine-rich address sequence.

DNA polymerization in the absence of exonucleolytic proofreading: in vivo and in vitro studies.

Drug-induced DNA repair: X-ray structure of a DNA-ditercalinium complex.

Quox-1, a quail homeobox gene expressed in the embryonic central nervous system, including the forebrain.

Generation of diverse high-affinity human monoclonal antibodies by repertoire cloning.

Calciseptine, a peptide isolated from black mamba venom, is a specific blocker of the L-type calcium channel.

Methotrexate inhibits neutrophil function by stimulating adenosine release from connective tissue cells.

A constitutively active holoenzyme form of the cAMP-dependent protein kinase.

Genetic organization and diversity of the hepatitis C virus.

Multiple forms of mRNA encoding human pregnancy-associated endometrial alpha 2-globulin, a beta-lactoglobulin homologue.

TTA codons in some genes prevent their expression in a class of developmental, antibiotic-negative, Streptomyces mutants.

Restricted T-cell receptor V beta gene usage by myelin basic protein-specific T-cell clones in multiple sclerosis: predominant genes vary in individuals.

Proton transfer is rate-limiting for translocation of precursor proteins by the Escherichia coli translocase.

Gene I, a potential cell-to-cell movement locus of cauliflower mosaic virus, encodes an RNA-binding protein.

Coexpression of the genes for platelet-derived growth factor B-chain receptor and macrophage colony-stimulating factor 1 receptor during monocytic differentiation.

Regional differences in calcium-release channels from heart.

A self-assembling protein kinase C inhibitor.

RNA-binding domain of the A protein component of the U1 small nuclear ribonucleoprotein analyzed by NMR spectroscopy is structurally similar to ribosomal proteins.

High level expression in Escherichia coli of soluble, enzymatically active schistosomal hypoxanthine/guanine phosphoribosyltransferase and trypanosomal ornithine decarboxylase.

Cloning and molecular characterization of the murine macrophage "68-kDa" protein kinase C substrate and its regulation by bacterial lipopolysaccharide.

Stearoyl-acyl-carrier-protein desaturase from higher plants is structurally unrelated to the animal and fungal homologs.

Characterization of a nuclear protein that binds to three elements within the silencer region of a bean chalcone synthase gene promoter.

Epidermal growth factor (EGF) receptor T669 peptide kinase from 3T3-L1 cells is an EGF-stimulated "MAP" kinase.

The ubiquitous glucose transporter GLUT-1 belongs to the glucose-regulated protein family of stress-inducible proteins.

Murine erythroleukemia cell line GM979 contains factors that can activate silent chromosomal human gamma-globin genes.

Erythropoietin receptors induced by dimethyl sulfoxide exhibit positive cooperativity associated with an amplified biologic response.

Interspecific gene flow in sympatric oaks.

Development of a possible nonmammalian test system for radiation-induced germ-cell mutagenesis using a fish, the Japanese medaka (Oryzias latipes).

Primary structure and ontogeny of an avian CD3 transcript.

Primary structure of the precursor for the sea anemone neuropeptide Antho-RFamide (less than Glu-Gly-Arg-Phe-NH2).

Receptors of the serotonin 1C subtype expressed from cloned DNA mediate the closing of K+ membrane channels encoded by brain mRNA.

Chemiluminescence detection of proteins from single cells.

Regulation of rhodopsin kinase by autophosphorylation.

Involvement of the cell cycle-regulated nuclear factor HiNF-D in cell growth control of a human H4 histone gene during hepatic development in transgenic mice.

Primary structures of the precursor and mature forms of stearoyl-acyl carrier protein desaturase from safflower embryos and requirement of ferredoxin for enzyme activity.

The reaction of hydroxylamine with bacteriorhodopsin studied with mutants that have altered photocycles: selective reactivity of different photointermediates.

Nature and functional implications of the cytochrome a3 transients after photodissociation of CO-cytochrome oxidase.

CCAAT/enhancer binding protein gene promoter: binding of nuclear factors during differentiation of 3T3-L1 preadipocytes.

Immunological suppression by human CD8+ T cells is receptor dependent and HLA-DQ restricted.

Evidence for thymopoietin and thymopoietin/alpha-bungarotoxin/nicotinic receptors within the brain.

Distinct muscarinic receptors inhibit release of gamma-aminobutyric acid and excitatory amino acids in mammalian brain.

Evolution of parasitism: kinetoplastid protozoan history reconstructed from mitochondrial rRNA gene sequences.

N-(Fluorenyl-9-methoxycarbonyl) amino acids, a class of antiinflammatory agents with a different mechanism of action

Increased expression of a 58-kDa protein kinase leads to changes in the CHO cell cycle

Molecular cloning and characterization of interferon α/β response element binding factors of the murine (2′-5′)oligoadenylate synthetase ME-12 gene

Host genes that influence transposition in yeast: The abundance of a rare tRNA regulates Ty1 transposition frequency

Year: 1991, Volume: 88, Issue: 5

Year: 1991, Volume: 88, Issue: 4

Year: 1991, Volume: 88, Issue: 3

Year: 1991, Volume: 88, Issue: 2

Year: 1991, Volume: 88, Issue: 1

Year: 1990, Volume: 87

Year: 1989, Volume: 86

Year: 1988, Volume: 85

Year: 1987, Volume: 84

Year: 1986, Volume: 83

Year: 1985, Volume: 82

Year: 1984, Volume: 81

Year: 1983, Volume: 80

Year: 1982, Volume: 79

Year: 1981, Volume: 78

Year: 1980, Volume: 77

Year: 1979, Volume: 76

Year: 1978, Volume: 75

Year: 1977, Volume: 74

Year: 1976, Volume: 73

Year: 1975, Volume: 72

Year: 1974, Volume: 71

Year: 1973, Volume: 70

Year: 1972, Volume: 69

Year: 1971, Volume: 68

Year: 1970, Volume: 67

Year: 1970, Volume: 66

Year: 1970, Volume: 65

Year: 1969, Volume: 64

Year: 1969, Volume: 63

Year: 1969, Volume: 62

Year: 1968, Volume: 61

Year: 1968, Volume: 60

Year: 1968, Volume: 59

Year: 1967, Volume: 58

Year: 1967, Volume: 57

Year: 1966, Volume: 56

Year: 1966, Volume: 55

Year: 1965, Volume: 54

Year: 1965, Volume: 53

Year: 1964, Volume: 52

Year: 1964, Volume: 51

Year: 1963, Volume: 50

Year: 1963, Volume: 49

Year: 1962, Volume: 48

Year: 1961, Volume: 47

Year: 1960, Volume: 46

Year: 1959, Volume: 45

Year: 1958, Volume: 44

Year: 1957, Volume: 43

Year: 1956, Volume: 42

Year: 1955, Volume: 41

Year: 1954, Volume: 40

Year: 1953, Volume: 39

Year: 1952, Volume: 38

Year: 1951, Volume: 37

Year: 1950, Volume: 36

Year: 1949, Volume: 35

Year: 1948, Volume: 34

Year: 1947, Volume: 33

Year: 1946, Volume: 32

Year: 1945, Volume: 31

Year: 1944, Volume: 30

Year: 1943, Volume: 29

Year: 1942, Volume: 28

Year: 1941, Volume: 27

Year: 1940, Volume: 26

Year: 1939, Volume: 25

Year: 1938, Volume: 24

Year: 1937, Volume: 23

Year: 1936, Volume: 22

Year: 1935, Volume: 21

Year: 1934, Volume: 20

Year: 1933, Volume: 19

Year: 1932, Volume: 18

Year: 1931, Volume: 17

Year: 1930, Volume: 16

Year: 1929, Volume: 15

Year: 1928, Volume: 14

Year: 1927, Volume: 13

Year: 1926, Volume: 12

Year: 1925, Volume: 11

Year: 1924, Volume: 10

Year: 1923, Volume: 9

Year: 1922, Volume: 8

Year: 1921, Volume: 7

Year: 1920, Volume: 6

Year: 1919, Volume: 5

Year: 1918, Volume: 4

Year: 1917, Volume: 3

Year: 1916, Volume: 2

Year: 1915, Volume: 1

Stearoyl-acyl-carrier-protein desaturase from higher plants is structurally unrelated to the animal and fungal homologs.

Content Provider	PubMed Central
Author	Shanklin, J. Somerville, C.
Abstract	Stearoyl-acyl-carrier-protein (ACP) desaturase (EC 1.14.99.6) was purified to homogeneity from avocado mesocarp, and monospecific polyclonal antibodies directed against the protein were used to isolate full-length cDNA clones from Ricinus communis (castor) seed and Cucumis sativus (cucumber). The nucleotide sequence of the castor clone pRCD1 revealed an open reading frame of 1.2 kilobases encoding a 396-amino acid protein of 45 kDa. The cucumber clone pCSD1 encoded a homologous 396-amino acid protein with 88% amino acid identity to the castor clone. Expression of pRCD1 in Saccharomyces cerevisiae resulted in the accumulation of a functional stearoyl-ACP desaturase, demonstrating that the introduction of this single gene product was sufficient to confer soluble desaturase activity to yeast. There was no detectable identity between the deduced amino acid sequences of the castor delta 9-stearoyl-ACP desaturase and either the delta 9-stearoyl-CoA desaturase from rat or yeast or the delta 12 desaturase from Synechocystis, suggesting that these enzymes may have evolved independently. However, there was a 48-residue region of 29% amino acid sequence identity between residues 53 and 101 of the castor desaturase and the proximal border of the dehydratase region of the fatty acid synthase from yeast. Stearoyl-ACP mRNA was present at substantially higher levels in developing seeds than in leaf and root tissue, suggesting that expression of the delta 9 desaturase is developmentally regulated.
Starting Page	2510
File Format	PDF
ISSN	10916490
e-ISSN	10916490
Journal	Proceedings of the National Academy of Sciences of the United States of America
Issue Number	6
Volume Number	88
Language	English
Publisher Date	1991-03-15
Access Restriction	Open
Subject Keyword	Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Multidisciplinary

Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302

See location in the Map
03222 282435
Mail: support@ndl.gov.in

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in