WebSite Logo
  • Content
  • Similar Resources
  • Metadata
  • Cite This
  • Language
    অসমীয়া বাংলা भोजपुरी डोगरी English ગુજરાતી हिंदी ಕನ್ನಡ
    Khasi कोंकणी मैथिली മലയാളം ꯃꯤꯇꯩ ꯂꯣꯟ मराठी Mizo नेपाली
    ଓଡ଼ିଆ ਪੰਜਾਬੀ संस्कृत ᱥᱟᱱᱛᱟᱲᱤ सिन्धी தமிழ் తెలుగు اردو
  • Log-in
  • Fullscreen
Log-in
Do not have an account? Register Now
Forgot your password? Account recovery
  1. Current Biology
  2. Year: 2016, Volume: 26
  3. Year: 2016, Volume: 26, Issue: 7
  4. Ancient Anxiety Pathways Influence Drosophila Defense Behaviors
Loading...

Please wait, while we are loading the content...

Year: 2016, Volume: 26
Year: 2016, Volume: 26, Issue: 12
Year: 2016, Volume: 26, Issue: 11
Year: 2016, Volume: 26, Issue: 9
Year: 2016, Volume: 26, Issue: 8
Year: 2016, Volume: 26, Issue: 7
Direct and indirect dorsolateral striatum pathways reinforce different action strategies
Neural Correlates of Decision Thresholds in the Human Subthalamic Nucleus
Ancient Anxiety Pathways Influence Drosophila Defense Behaviors
Year: 2016, Volume: 26, Issue: 6
Year: 2016, Volume: 26, Issue: 5
Year: 2016, Volume: 26, Issue: 4
Year: 2016, Volume: 26, Issue: 3
Year: 2016, Volume: 26, Issue: 2
Year: 2016, Volume: 26, Issue: 1
Year: 2015, Volume: 25
Year: 2014, Volume: 24
Year: 2013, Volume: 23
Year: 2012, Volume: 22
Year: 2011, Volume: 21
Year: 2010, Volume: 20
Year: 2009, Volume: 19
Year: 2008, Volume: 18
Year: 2007, Volume: 17
Year: 2006, Volume: 16

Similar Documents

...
Distinct retinal pathways drive spatial orientation behaviors in zebrafish navigation

Article

...
Ecdysone receptor acts in fruitless-expressing neurons to mediate Drosophila courtship behaviors

Article

...
Endogenous RNA Interference Provides a Somatic Defense against Drosophila Transposons

Article

...
The influence of light on temperature preference in Drosophila

Article

...
Functional Divergence Caused by Ancient Positive Selection of a Drosophila Hybrid Incompatibility Locus

Article

...
Ancient and Novel Small RNA Pathways Compensate for the Loss of piRNAs in Multiple Independent Nematode Lineages

Article

...
Sugar receptors in Drosophila

Article

...
Deconstructing Memory in Drosophila

Article

...
Converging Pathways in Lifespan Regulation

Article

Ancient Anxiety Pathways Influence Drosophila Defense Behaviors

Content Provider PubMed Central
Author Mohammad, Farhan Aryal, Sameer Ho, Joses Stewart, James charles Norman, Nurul ayuni Tan, Teng li Agnese, Eisaka Adam, Claridge-chang
Copyright Year 2016
Abstract Anxiety helps us anticipate and assess potential danger in ambiguous situations [1, 2, 3]; however, the anxiety disorders are the most prevalent class of psychiatric illness [4, 5, 6]. Emotional states are shared between humans and other animals [7], as observed by behavioral manifestations [8], physiological responses [9], and gene conservation [10]. Anxiety research makes wide use of three rodent behavioral assays—elevated plus maze, open field, and light/dark box—that present a choice between sheltered and exposed regions [11]. Exposure avoidance in anxiety-related defense behaviors was confirmed to be a correlate of rodent anxiety by treatment with known anxiety-altering agents [12, 13, 14] and is now used to characterize anxiety systems. Modeling anxiety with a small neurogenetic animal would further aid the elucidation of its neuronal and molecular bases. Drosophila neurogenetics research has elucidated the mechanisms of fundamental behaviors and implicated genes that are often orthologous across species. In an enclosed arena, flies stay close to the walls during spontaneous locomotion [15, 16], a behavior proposed to be related to anxiety [17]. We tested this hypothesis with manipulations of the GABA receptor, serotonin signaling, and stress. The effects of these interventions were strikingly concordant with rodent anxiety, verifying that these behaviors report on an anxiety-like state. Application of this method was able to identify several new fly anxiety genes. The presence of conserved neurogenetic pathways in the insect brain identifies Drosophila as an attractive genetic model for the study of anxiety and anxiety-related disorders, complementing existing rodent systems.
Related Links http://dx.doi.org/10.1016/j.cub.2016.02.031
Ending Page 986
Page Count 6
Starting Page 981
File Format PDF
ISSN 09609822
e-ISSN 18790445
Journal Current Biology
Issue Number 7
Volume Number 26
Language English
Publisher Cell Press
Publisher Date 2016-04-01
Access Restriction Open
Rights Holder Cell Press
Subject Keyword Biochemistry, Genetics and Molecular Biology(all) Agricultural and Biological Sciences(all) Research in Higher Education
Content Type Text
Resource Type Article
Subject Neuroscience Biochemistry, Genetics and Molecular Biology Agricultural and Biological Sciences
  • About
  • Disclaimer
  • Feedback
  • Sponsor
  • Contact
About National Digital Library of India (NDLI)
NDLI logo

National Digital Library of India (NDLI) is a virtual repository of learning resources which is not just a repository with search/browse facilities but provides a host of services for the learner community. It is sponsored and mentored by Ministry of Education, Government of India, through its National Mission on Education through Information and Communication Technology (NMEICT). Filtered and federated searching is employed to facilitate focused searching so that learners can find the right resource with least effort and in minimum time. NDLI provides user group-specific services such as Examination Preparatory for School and College students and job aspirants. Services for Researchers and general learners are also provided. NDLI is designed to hold content of any language and provides interface support for 10 most widely used Indian languages. It is built to provide support for all academic levels including researchers and life-long learners, all disciplines, all popular forms of access devices and differently-abled learners. It is designed to enable people to learn and prepare from best practices from all over the world and to facilitate researchers to perform inter-linked exploration from multiple sources. It is developed, operated and maintained from Indian Institute of Technology Kharagpur.

Learn more about this project from here.

Disclaimer

NDLI is a conglomeration of freely available or institutionally contributed or donated or publisher managed contents. Almost all these contents are hosted and accessed from respective sources. The responsibility for authenticity, relevance, completeness, accuracy, reliability and suitability of these contents rests with the respective organization and NDLI has no responsibility or liability for these. Every effort is made to keep the NDLI portal up and running smoothly unless there are some unavoidable technical issues.

Feedback

Sponsor

Ministry of Education, through its National Mission on Education through Information and Communication Technology (NMEICT), has sponsored and funded the National Digital Library of India (NDLI) project.

Contact National Digital Library of India
Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302
See location in the Map
03222 282435
Mail: support@ndl.gov.in
Sl. Authority Responsibilities Communication Details
1 Ministry of Education (GoI),
Department of Higher Education
Sanctioning Authority https://www.education.gov.in/ict-initiatives
2 Indian Institute of Technology Kharagpur Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project https://www.iitkgp.ac.in
3 National Digital Library of India Office, Indian Institute of Technology Kharagpur The administrative and infrastructural headquarters of the project Dr. B. Sutradhar  bsutra@ndl.gov.in
4 Project PI / Joint PI Principal Investigator and Joint Principal Investigators of the project Dr. B. Sutradhar  bsutra@ndl.gov.in
Prof. Saswat Chakrabarti  will be added soon
5 Website/Portal (Helpdesk) Queries regarding NDLI and its services support@ndl.gov.in
6 Contents and Copyright Issues Queries related to content curation and copyright issues content@ndl.gov.in
7 National Digital Library of India Club (NDLI Club) Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach clubsupport@ndl.gov.in
8 Digital Preservation Centre (DPC) Assistance with digitizing and archiving copyright-free printed books dpc@ndl.gov.in
9 IDR Setup or Support Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops idr@ndl.gov.in
Cite this Content
Loading...