NDLI: Associations between Carotid Artery Plaque Score, Carotid Hemodynamics and Coronary Heart Disease

Content Provider	PubMed Central
Author	Zhang, Huiping Liu, Mengxue Ren, Tiantian Wang, Xiangqian Liu, Dandan Xu, Mingliang Han, Lingfei Wu, Zewei Li, Haibo Zhu, Yu Wen, Yufeng Sun, Wenjie
Editor	Tchounwou, Paul B.
Copyright Year	2015
Abstract	Background: The carotid artery plaque score (PS) is an independent predictor of Coronary Heart Disease (CHD). This study aims to evaluate the combination of PS and carotid hemodynamics to predict CHD. Methods: A total of 476 patients who underwent carotid ultrasonography and coronary angiography were divided into two groups depending on the presence of CHD. PS, carotid intima-media thickness, and carotid blood flow were measured. Receiver operating characteristic curve analysis was performed to establish the best prediction model for CHD presence. Results: Age, sex, carotid intima-media thickness of internal carotid artery and carotid bifurcation, PS, peak systolic velocity (PSA) of right internal carotid artery (RICA), and most resistance index data were significantly related with the presence of CHD. The area under the curve for a collective model, which included factors of the PS, carotid hemodynamics and age, was significantly higher than the other model. Age, PS, and PSA of RICA were significant contributors for predicting CHD presence. Conclusions: The model of PS and PSA of RICA has greater predictive value for CHD than PS alone. Adding age to PS and PSA of RICA further improves predictive value over PS alone.
Related Links	http://dx.doi.org/10.3390/ijerph121114275
Ending Page	14284
Page Count	10
Starting Page	14275
File Format	PDF
ISSN	16604601
e-ISSN	16604601
Journal	International Journal of Environmental Research and Public Health
Issue Number	11
Volume Number	12
Language	English
Publisher	MDPI
Publisher Date	2015-11-01
Access Restriction	Open
Rights Holder	MDPI
Subject Keyword	Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Health, Toxicology and Mutagenesis Pollution Public Health, Environmental and Occupational Health

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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