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| Content Provider | PubMed Central |
|---|---|
| Author | Chen, Xiaohong Fu, Chengtao Liu, Jia Shan, Lei Liu, Chenglin |
| Copyright Year | 2015 |
| Abstract | Aim: This study was to investigate the epidemiological and clinical features of acute hepatitis B. Methods: A retrospective study of 177 acute hepatitis B patients with an average age of 36.03 years and range of 7-62 years was conducted from Jan 2005 to Feb 2011. The epidemiological and clinical parameters were investigated. The serological markers and biochemical tests were examined. Results: 76.84% (n = 136) patients were icteric type, while 23.16% (n = 41) were non-icteric type. Other clinical manifestations for acute hepatitis patients included fatigue (82.49%), gastrointestinal symptoms (66.10%), yellowish discoloration of skin and sclera, fever (31.07%), rash 10 (5.65%), joint pain (2.82%) and headache (1.69%). One case presented with acute renal failure associated with acute hepatitis B. Nine cases suffered from fulminant hepatitis. After treatment, hepatic function was significantly improved (P < 0.05). For serological markers, 54 (30.51%) and 119 (67.23%) patients had HBsAg and HBV-DNA seroconversion respectively. Four deaths occurred due to the severe complications associated by acute infection of HBV during half a year period follow up. Conclusions: Adult males with occupation of workers and farmers are the high-risk population of acute hepatitis B in China. Several complications associated with acute hepatitis B should be noticed. |
| Ending Page | 16657 |
| Starting Page | 16652 |
| File Format | |
| ISSN | 19405901 |
| e-ISSN | 19405901 |
| Journal | International Journal of Clinical and Experimental Medicine |
| Issue Number | 9 |
| Volume Number | 8 |
| Language | English |
| Publisher | e-Century Publishing Corporation |
| Publisher Date | 2015-09-15 |
| Access Restriction | Open |
| Rights Holder | e-Century Publishing Corporation |
| Subject Keyword | Research in Higher Education |
| Content Type | Text |
| Resource Type | Article |
| Subject | Biochemistry, Genetics and Molecular Biology |
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