NDLI: Loop Diuretics in Clinical Practice

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Loop Diuretics in Clinical Practice

Content Provider	PubMed Central
Author	Oh, Se Won Han, Sang Youb
Copyright Year	2015
Abstract	Diuretics are commonly used to control edema across various clinical fields. Diuretics inhibit sodium reabsorption in specific renal tubules, resulting in increased urinary sodium and water excretion. Loop diuretics are the most potent diuretics. In this article, we review five important aspects of loop diuretics, in particular furosemide, which must be considered when prescribing this medicine: (1) oral versus intravenous treatment, (2) dosage, (3) continuous versus bolus infusion, (4) application in chronic kidney disease patients, and (5) side effects. The bioavailability of furosemide differs between oral and intravenous therapy. Additionally, the threshold and ceiling doses of furosemide differ according to the particular clinical condition of the patient, for example in patients with severe edema or chronic kidney disease. To maximize the efficiency of furosemide, a clear understanding of how the mode of delivery will impact bioavailability and the required dosage is necessary.
Related Links	http://dx.doi.org/10.5049/EBP.2015.13.1.17
Starting Page	17
File Format	PDF
ISSN	20929935
e-ISSN	20929935
Journal	Electrolytes & Blood Pressure : E & BP
Issue Number	1
Volume Number	13
Language	English
Publisher	The Korean Society of Electrolyte Metabolism
Publisher Date	2015-06-01
Access Restriction	Open
Rights Holder	The Korean Society of Electrolyte Metabolism
Subject Keyword	Research in Higher Education
Content Type	Text
Resource Type	Article

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