NDLI: Simultaneous nano- and micro-scale control of nanofibrous microspheres self-assembled from star-shaped polymers

Content Provider	PubMed Central
Author	Zhang, Zhanpeng Marson, Ryan L. Ge, Zhishen Glotzer, Sharon C. Ma, Peter X.
Abstract	The mechanism underlying the multi-scale self-assembly of star-shaped polymers into non-hollow, hollow, and spongy nanofibrous microspheres is reported. Star-shaped poly(L-lactic acid) polymers with varying arm-numbers and arm-lengths are synthesized, dissolved in tetrahydrofuran, emulsified in glycerol, and thermally-induced to phase separate, resulting in microspheres that are either smooth or fibrous on the nano-scale, and either non-hollow, hollow, or spongy on the micro-scale. Molecular architecture and the hydroxyl density are shown to control assembly and morphology at both nano- and micro-scales. Nanofibers form only when the arm length is sufficiently long, while an increase in hydroxyl density causes the microspheres to change from non-hollow to hollow to spongy. We demonstrate via both experiments of capping or doubling the hydroxyl end groups and dissipative particle dynamics simulations that the affinity of hydroxyl to glycerol is critical to stabilizing the micro-scale structure. A “phase diagram” was constructed for the six types of microspheres in relation to the molecular structures of the star-shaped polymers. The proposed mechanism explains how star-shaped polymers self-assemble into various microspheres, and guides us to simultaneously control both nano- and micro-features of the microspheres.
Related Links	http://dx.doi.org/10.1002/adma.201501329
Ending Page	3952
Page Count	6
Starting Page	3947
File Format	PDF
ISSN	15214095
e-ISSN	15214095
Journal	Advanced materials (Deerfield Beach, Fla.)
Issue Number	26
Volume Number	27
Language	English
Publisher Date	2015-07-08
Access Restriction	Open
Subject Keyword	Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Nanoscience and Nanotechnology Mechanics of Materials Mechanical Engineering

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