NDLI: Exercise and type 2 diabetes: molecular mechanisms regulating glucose uptake in skeletal muscle

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Exercise and type 2 diabetes: molecular mechanisms regulating glucose uptake in skeletal muscle

Content Provider	PubMed Central
Author	Stanford, Kristin I. Goodyear, Laurie J.
Copyright Year	2014
Abstract	Exercise is a well-established tool to prevent and combat type 2 diabetes. Exercise improves whole body metabolic health in people with type 2 diabetes, and adaptations to skeletal muscle are essential for this improvement. An acute bout of exercise increases skeletal muscle glucose uptake, while chronic exercise training improves mitochondrial function, increases mitochondrial biogenesis, and increases the expression of glucose transporter proteins and numerous metabolic genes. This review focuses on the molecular mechanisms that mediate the effects of exercise to increase glucose uptake in skeletal muscle.
Related Links	http://dx.doi.org/10.1152/advan.00080.2014
Ending Page	314
Page Count	7
Starting Page	308
File Format	PDF
ISSN	15221229
e-ISSN	15221229
Journal	Advances in Physiology Education
Issue Number	4
Volume Number	38
Language	English
Publisher	American Physiological Society
Publisher Date	2014-12-01
Access Restriction	Open
Rights Holder	American Physiological Society
Subject Keyword	Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Physiology Education

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