NDLI: An integrated overview of spatiotemporal organization and regulation in mitosis in terms of the proteins in the functional supercomplexes

Content Provider	PubMed Central
Author	Zheng, Yueyuan Guo, Junjie Li, Xu Xie, Yubin Hou, Mingming Fu, Xuyang Dai, Shengkun Diao, Rucheng Miao, Yanyan Ren, Jian
Copyright Year	2014
Abstract	Eukaryotic cells may divide via the critical cellular process of cell division/mitosis, resulting in two daughter cells with the same genetic information. A large number of dedicated proteins are involved in this process and spatiotemporally assembled into three distinct super-complex structures/organelles, including the centrosome/spindle pole body, kinetochore/centromere and cleavage furrow/midbody/bud neck, so as to precisely modulate the cell division/mitosis events of chromosome alignment, chromosome segregation and cytokinesis in an orderly fashion. In recent years, many efforts have been made to identify the protein components and architecture of these subcellular organelles, aiming to uncover the organelle assembly pathways, determine the molecular mechanisms underlying the organelle functions, and thereby provide new therapeutic strategies for a variety of diseases. However, the organelles are highly dynamic structures, making it difficult to identify the entire components. Here, we review the current knowledge of the identified protein components governing the organization and functioning of organelles, especially in human and yeast cells, and discuss the multi-localized protein components mediating the communication between organelles during cell division.
Related Links	http://dx.doi.org/10.3389/fmicb.2014.00573
Starting Page	573
File Format	PDF
ISSN	1664302X
e-ISSN	1664302X
Journal	Frontiers in Microbiology
Volume Number	5
Language	English
Publisher	Frontiers Media S.A.
Publisher Date	2014-10-01
Access Restriction	Open
Rights Holder	Frontiers Media S.A.
Subject Keyword	Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Microbiology Microbiology (medical)

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Quorum-sensing regulation in staphylococci—an overview

Spatiotemporal Regulation of the Anaphase-Promoting Complex in Mitosis

Lipids in the Assembly of Membrane Proteins and Organization of Protein Supercomplexes

Intrinsic Regulation of Spatiotemporal Organization within the Suprachiasmatic Nucleus

An overview of malaria transmission from the perspective of AmazonAnopheles vectors

The Protein Information Resource: an integrated public resource of functional annotation of proteins

Using supported bilayers to study the spatiotemporal organization of membrane bound proteins

Diversity Among Cyanobacterial Photosystem I Oligomers

Probiotics and Atopic Dermatitis: An Overview

An integrated overview of spatiotemporal organization and regulation in mitosis in terms of the proteins in the functional supercomplexes

Similar Documents

Quorum-sensing regulation in staphylococci—an overview

Spatiotemporal Regulation of the Anaphase-Promoting Complex in Mitosis

Lipids in the Assembly of Membrane Proteins and Organization of Protein Supercomplexes

Intrinsic Regulation of Spatiotemporal Organization within the Suprachiasmatic Nucleus

An overview of malaria transmission from the perspective of AmazonAnopheles vectors

The Protein Information Resource: an integrated public resource of functional annotation of proteins

Using supported bilayers to study the spatiotemporal organization of membrane bound proteins

Diversity Among Cyanobacterial Photosystem I Oligomers

Probiotics and Atopic Dermatitis: An Overview

An integrated overview of spatiotemporal organization and regulation in mitosis in terms of the proteins in the functional supercomplexes