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| Content Provider | PubMed Central |
|---|---|
| Author | Hyung, An Jae Goo, Eunhye Kim, Hongsup Seo, Young-su Hwang, Ingyu |
| Abstract | Quorum sensing (QS) is a coordinated gene-regulation system that controls bacterial social behaviors, such as virulence, motility, biofilm formation, and toxin production, in response to cell density. Acyl-homoserine lactone-mediated QS coordinates cooperativity between individual cells of many Proteobacteria species. QS may also control nutrient acquisition and help maintain the homeostatic primary metabolism of individuals in a cooperative population. Here, we show that QS restricts glucose uptake and slows primary metabolism of individual cells in crowded conditions. QS-deficient cells experienced serious physiological challenges under similar conditions, indicating that QS functions as a means to ensure efficient energy and resource utilization of individuals in crowded environments. |
| Related Links | http://dx.doi.org/10.1073/pnas.1412431111 |
| Ending Page | 14917 |
| Page Count | 6 |
| Starting Page | 14912 |
| File Format | |
| ISSN | 10916490 |
| e-ISSN | 10916490 |
| Journal | Proceedings of the National Academy of Sciences of the United States of America |
| Issue Number | 41 |
| Volume Number | 111 |
| Language | English |
| Publisher | National Academy of Sciences |
| Publisher Date | 2014-10-14 |
| Access Restriction | Open |
| Rights Holder | National Academy of Sciences |
| Subject Keyword | Research in Higher Education |
| Content Type | Text |
| Resource Type | Article |
| Subject | Multidisciplinary |
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