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| Content Provider | PubMed Central |
|---|---|
| Author | Palmer, Alan M. |
| Copyright Year | 2013 |
| Abstract | Multiple sclerosis (MS) is a neurodegenerative disease with a major inflammatory component that constitutes the most common progressive and disabling neurological condition in young adults. Injectable immunomodulatory medicines such as interferon drugs and glatiramer acetate have dominated the MS market for over the past two decades but this situation is set to change. This is because of: (i) patent expirations, (ii) the introduction of natalizumab, which targets the interaction between leukocytes and the blood–CNS barrier, (iii) the launch of three oral immunomodulatory drugs (fingolimod, dimethyl fumarate and teriflunomide), with another (laquinimod) under regulatory review and (iv) a number of immunomodulatory monoclonal antibodies (alemtuzumab, daclizumab and ocrelizumab) about to enter the market. Current and emerging medicines are reviewed and their impact on people with MS considered. |
| Related Links | http://dx.doi.org/10.1111/bcp.12285 |
| Ending Page | 43 |
| Page Count | 11 |
| Starting Page | 33 |
| File Format | |
| ISSN | 13652125 |
| e-ISSN | 13652125 |
| Journal | British Journal of Clinical Pharmacology |
| Issue Number | 1 |
| Volume Number | 78 |
| Language | English |
| Publisher | Blackwell Science Inc |
| Publisher Date | 2014-07-01 |
| Access Restriction | Open |
| Rights Holder | Blackwell Science Inc |
| Subject Keyword | Research in Higher Education |
| Content Type | Text |
| Resource Type | Article |
| Subject | Pharmacology Pharmacology (medical) |
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