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| Content Provider | PubMed Central |
|---|---|
| Author | Ahn, Jem Ma Paik, Yong-han Kim, So Hyun Lee, Jun Hee Cho, Ju Yeon Sohn, Won Gwak, Geum-youn Choi, Moon Seok Lee, Joon Hyeok Koh, Kwang Cheol Paik, Seung Woon Yoo, Byung Chul |
| Copyright Year | 2014 |
| Abstract | High prevalence of diabetes mellitus in patients with liver cirrhosis has been reported in many studies. The aim of our study was to evaluate the relationship of hepatic fibrosis and steatosis assessed by transient elastography with diabetes in patients with chronic liver disease. The study population consisted of 979 chronic liver disease patients. Liver fibrosis and steatosis were assessed by liver stiffness measurement (LSM) and controlled attenuation parameter (CAP) on transient elastography. Diabetes was diagnosed in 165 (16.9%) of 979 patients. The prevalence of diabetes had significant difference among the etiologies of chronic liver disease. Higher degrees of liver fibrosis and steatosis, assessed by LSM and CAP score, showed higher prevalence of diabetes (F0/1 [14%], F2/3 [18%], F4 [31%], P<0.001; S0/1 [15%], S2 [17%], S3 [26%], P=0.021). Multivariate analysis showed that the independent predictive risk factors for diabetes were hypertension (OR, 1.98; P=0.001), LSM F4 (OR, 1.86; P=0.010), male gender (OR, 1.60; P=0.027), and age>50 yr (OR, 1.52; P=0.046). The degree of hepatic fibrosis but not steatosis assessed by transient elastography has significant relationship with the prevalence of diabetes in patients with chronic liver disease. |
| Related Links | http://dx.doi.org/10.3346/jkms.2014.29.8.1113 |
| Ending Page | 1119 |
| Page Count | 7 |
| Starting Page | 1113 |
| File Format | |
| ISSN | 15986357 |
| e-ISSN | 15986357 |
| Journal | Journal of Korean Medical Science |
| Issue Number | 8 |
| Volume Number | 29 |
| Language | English |
| Publisher | The Korean Academy of Medical Sciences |
| Publisher Date | 2014-08-01 |
| Access Restriction | Open |
| Rights Holder | The Korean Academy of Medical Sciences |
| Subject Keyword | Research in Higher Education |
| Content Type | Text |
| Resource Type | Article |
| Subject | Medicine |
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