Please wait, while we are loading the content...
Please wait, while we are loading the content...
| Content Provider | PubMed Central |
|---|---|
| Author | Tarasub, Naovarat Junseecha, Thongbai Tarasub, Chinnawat Na, Ayutthaya Watcharaporn Devakul |
| Copyright Year | 2012 |
| Abstract | Curcumin, a biologically active compound from turmeric, and vitamin C act as a natural antioxidant and potent chemopreventive agent. The objective of the study was to investigate whether the combined pretreatment with curcumin and vitamin C offers more beneficial effects than that provided by either of them alone in reversing cadmium (Cd)- induced hepatotoxicity. For this purpose, 64 adult male Wistar rats, equally divided into control and seven treated groups, received either Cd (as CdCl2 5 mg/kg), curcumin 400 mg/kg, curcumin 200 or 400 mg/kg + CdCl2, vitamin C 100 mg/kg + CdCl2, curcumin 200 or 400 mg/kg + vitamin C + CdCl2. All groups were treated by gavage for 27 days. The results showed that Cd treatment increased significantly lipid peroxidation levels,decreased significantly the glutathione levels, increased significantly on metallothionein (MT) expressions including the degenerative changes of liver histological tissues were observed. The treatment of Cd-exposed rats with curcumin or vitamin C alone could not reverse Cd-induced the above changes. The combined treatment with curcumin along with vitamin C before Cd intoxication was more effective than that with either of them alone in reducing such changes and reverse the changes almost similar to that of control. In conclusion, the results demonstrated that the combined pretreatment with curcumin along with vitamin C could recover the alterations and offer more protection than curcumin or vitamin C alone against Cd hepatotoxicity. |
| Starting Page | 273 |
| File Format | |
| ISSN | 09760113 |
| e-ISSN | 09760113 |
| Journal | Journal of Basic and Clinical Pharmacy |
| Issue Number | 2 |
| Volume Number | 3 |
| Language | English |
| Publisher | Medknow Publications & Media Pvt Ltd |
| Publisher Date | 2012-03-01 |
| Access Restriction | Open |
| Rights Holder | Medknow Publications & Media Pvt Ltd |
| Subject Keyword | Research in Higher Education |
| Content Type | Text |
| Resource Type | Article |
National Digital Library of India (NDLI) is a virtual repository of learning resources which is not just a repository with search/browse facilities but provides a host of services for the learner community. It is sponsored and mentored by Ministry of Education, Government of India, through its National Mission on Education through Information and Communication Technology (NMEICT). Filtered and federated searching is employed to facilitate focused searching so that learners can find the right resource with least effort and in minimum time. NDLI provides user group-specific services such as Examination Preparatory for School and College students and job aspirants. Services for Researchers and general learners are also provided. NDLI is designed to hold content of any language and provides interface support for 10 most widely used Indian languages. It is built to provide support for all academic levels including researchers and life-long learners, all disciplines, all popular forms of access devices and differently-abled learners. It is designed to enable people to learn and prepare from best practices from all over the world and to facilitate researchers to perform inter-linked exploration from multiple sources. It is developed, operated and maintained from Indian Institute of Technology Kharagpur.
Learn more about this project from here.
NDLI is a conglomeration of freely available or institutionally contributed or donated or publisher managed contents. Almost all these contents are hosted and accessed from respective sources. The responsibility for authenticity, relevance, completeness, accuracy, reliability and suitability of these contents rests with the respective organization and NDLI has no responsibility or liability for these. Every effort is made to keep the NDLI portal up and running smoothly unless there are some unavoidable technical issues.
Ministry of Education, through its National Mission on Education through Information and Communication Technology (NMEICT), has sponsored and funded the National Digital Library of India (NDLI) project.
| Sl. | Authority | Responsibilities | Communication Details |
|---|---|---|---|
| 1 | Ministry of Education (GoI), Department of Higher Education |
Sanctioning Authority | https://www.education.gov.in/ict-initiatives |
| 2 | Indian Institute of Technology Kharagpur | Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project | https://www.iitkgp.ac.in |
| 3 | National Digital Library of India Office, Indian Institute of Technology Kharagpur | The administrative and infrastructural headquarters of the project | Dr. B. Sutradhar bsutra@ndl.gov.in |
| 4 | Project PI / Joint PI | Principal Investigator and Joint Principal Investigators of the project |
Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon |
| 5 | Website/Portal (Helpdesk) | Queries regarding NDLI and its services | support@ndl.gov.in |
| 6 | Contents and Copyright Issues | Queries related to content curation and copyright issues | content@ndl.gov.in |
| 7 | National Digital Library of India Club (NDLI Club) | Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach | clubsupport@ndl.gov.in |
| 8 | Digital Preservation Centre (DPC) | Assistance with digitizing and archiving copyright-free printed books | dpc@ndl.gov.in |
| 9 | IDR Setup or Support | Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops | idr@ndl.gov.in |
|
Loading...
|