NDLI: Early Trajectory of Psychiatric Symptoms after Traumatic Brain Injury: Relationship to Patient and Injury Characteristics

Please wait, while we are loading the content...

Post-Traumatic Hypoxia Is Associated with Prolonged Cerebral Cytokine Production, Higher Serum Biomarker Levels, and Poor Outcome in Patients with Severe Traumatic Brain Injury

Contribution of Psychological Trauma to Outcomes after Traumatic Brain Injury: Assaults versus Sporting Injuries

Vascular Endothelial Growth Factor Concentration in Chronic Subdural Hematoma Fluid Is Related to Computed Tomography Appearance and Exudation Rate

Recovery of Stress Response Coincides with Responsiveness to Voluntary Exercise after Traumatic Brain Injury

Temporal Course of Changes in Gene Expression Suggests a Cytokine-Related Mechanism for Long-Term Hippocampal Alteration after Controlled Cortical Impact

Year: 2014, Volume: 31, Issue: 6

Year: 2014, Volume: 31, Issue: 5

Year: 2014, Volume: 31, Issue: 4

Year: 2014, Volume: 31, Issue: 3

Year: 2014, Volume: 31, Issue: 2

Year: 2014, Volume: 31, Issue: 1

Year: 2013, Volume: 30

Year: 2012, Volume: 29

Year: 2011, Volume: 28

Year: 2010, Volume: 27

Year: 2009, Volume: 26

Year: 2008, Volume: 25

Year: 2007, Volume: 24

Year: 2006, Volume: 23

Year: 2005, Volume: 22

Year: 2003, Volume: 20

Year: 2002, Volume: 19

Year: 2000, Volume: 17

Early Trajectory of Psychiatric Symptoms after Traumatic Brain Injury: Relationship to Patient and Injury Characteristics

Content Provider	PubMed Central
Author	Hart, Tessa Benn, Emma K. T. Emilia, Bagiella Arenth, Patricia Dikmen, Sureyya Hesdorffer, Dale C. Novack, Thomas A. Ricker, Joseph H. Zafonte, Ross
Copyright Year	2014
Abstract	Psychiatric disturbance is common and disabling after traumatic brain injury (TBI). Few studies have investigated the trajectory of psychiatric symptoms in the first 6 months postinjury, when monitoring and early treatment might prevent persistent difficulties. The aim of this study was to examine the trajectory of psychiatric symptoms 1–6 months post-TBI, the patient/injury characteristics associated with changes, and characteristics predictive of persisting symptoms. A secondary analysis was performed on data from a clinical trial with three data collection points. Across eight centers, 872 participants with complicated mild to severe TBI were administered the Brief Symptom Inventory (BSI) at 30, 90, and 180 days postinjury. Mixed-effects models were used to assess longitudinal changes in the BSI Global Severity Index (GSI). Multi-variate logistic regression was used to assess predictors of clinically significant GSI elevations persisting to 6 months post-TBI. In general, GSI scores improved over time. Women improved faster than men; race/ethnicity was also significantly associated with rate of change, with Hispanics showing the most and African Americans the least improvement. Clinically significant psychiatric symptoms (caseness) occurred in 42% of the sample at 6 months, and more than one type of symptom was common. Significant predictors of caseness included African American race, age from 30 to 60 years, longer post-traumatic amnesia (PTA) duration, pre-TBI unemployment, and pre-TBI risky alcohol use. Findings indicate that psychiatric symptoms are common in the first 6 months post-TBI and frequently extend beyond the depression and anxiety symptoms that may be most commonly screened. Patients with longer PTA and preinjury alcohol misuse may need more intensive monitoring for symptom persistence.
Related Links	http://dx.doi.org/10.1089/neu.2013.3041
Ending Page	617
Page Count	8
Starting Page	610
File Format	PDF
ISSN	08977151
e-ISSN	15579042
Journal	Journal of Neurotrauma
Issue Number	7
Volume Number	31
Language	English
Publisher	Mary Ann Liebert, Inc.
Publisher Date	2014-04-01
Access Restriction	Open
Rights Holder	Mary Ann Liebert, Inc.
Subject Keyword	Clinical Neurology Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Neurology (clinical)

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Prediction of post-traumatic complaints after mild traumatic brain injury: early symptoms and biochemical markers

Neuroglobin Genetic Polymorphisms and Their Relationship to Functional Outcomes after Traumatic Brain Injury

Traumatic Injury to the Developing Brain: Emerging Relationship to Early Life Stress

Cognitive Reserve, Early Cognitive Screening, and Relationship to Long-Term Outcome after Severe Traumatic Brain Injury

The relationship between personality traits and health-related quality of life after mild-to-moderate traumatic brain injury

Patient Characterization Protocols for Psychophysiological Studies of Traumatic Brain Injury and Post-TBI Psychiatric Disorders

Do Sleep Problems Mediate the Relationship between Traumatic Brain Injury and Development of Mental Health Symptoms after Deployment?

Early Changes in the White Matter Microstructure and Connectome Underlie Cognitive Deficit and Depression Symptoms After Mild Traumatic Brain Injury

Multidisciplinary approach to psychiatric symptoms in mild traumatic brain injury: Complex sequelae necessitate a cadre of treatment providers

Early Trajectory of Psychiatric Symptoms after Traumatic Brain Injury: Relationship to Patient and Injury Characteristics

Similar Documents

Prediction of post-traumatic complaints after mild traumatic brain injury: early symptoms and biochemical markers

Neuroglobin Genetic Polymorphisms and Their Relationship to Functional Outcomes after Traumatic Brain Injury

Traumatic Injury to the Developing Brain: Emerging Relationship to Early Life Stress

Cognitive Reserve, Early Cognitive Screening, and Relationship to Long-Term Outcome after Severe Traumatic Brain Injury

The relationship between personality traits and health-related quality of life after mild-to-moderate traumatic brain injury

Patient Characterization Protocols for Psychophysiological Studies of Traumatic Brain Injury and Post-TBI Psychiatric Disorders

Do Sleep Problems Mediate the Relationship between Traumatic Brain Injury and Development of Mental Health Symptoms after Deployment?

Early Changes in the White Matter Microstructure and Connectome Underlie Cognitive Deficit and Depression Symptoms After Mild Traumatic Brain Injury

Multidisciplinary approach to psychiatric symptoms in mild traumatic brain injury: Complex sequelae necessitate a cadre of treatment providers

Early Trajectory of Psychiatric Symptoms after Traumatic Brain Injury: Relationship to Patient and Injury Characteristics