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Acyl Hydrazides as Peptoid Sub-monomers
| Content Provider | PubMed Central |
|---|---|
| Author | Sarma, Bani Kanta Muhammed, Yousufuddin Kodadek, Thomas |
| Abstract | The use of acyl hydrazides as peptoid sub-monomers is investigated. We demonstrate here that azapeptoids derived entirely from acyl hydrazides can be made conveniently and efficiently using standard peptoid sub-monomer chemistry. Structural studies reveal that the main chain amide bond in these molecules predominantly adopts a trans conformation. A high-quality one bead one compound library of tetramers was made by split and pool synthesis and we found that the identity of the molecule on a single bead could be determined by tandem MALDI mass spectrometry. |
| Related Links | http://dx.doi.org/10.1039/c1cc12750k |
| File Format | |
| ISSN | 13597345 |
| e-ISSN | 1364548X |
| Journal | Chemical communications (Cambridge, England) |
| Issue Number | 38 |
| Volume Number | 47 |
| Language | English |
| Publisher Date | 2011-01-01 |
| Access Restriction | Open |
| Subject Keyword | Materials Chemistry Electronic, Optical and Magnetic Materials Chemistry(all) Surfaces, Coatings and Films Metals and Alloys Ceramics and Composites Catalysis Research in Higher Education |
| Content Type | Text |
| Resource Type | Article |
| Subject | Ceramics and Composites Chemistry Surfaces, Coatings and Films Materials Chemistry Metals and Alloys Electronic, Optical and Magnetic Materials Catalysis |