Loading...
Please wait, while we are loading the content...
Similar Documents
The Dendritic Cell Lineage: Ontogeny and Function of Dendritic Cells and Their Subsets in the Steady State and the Inflamed Setting
| Content Provider | PubMed Central |
|---|---|
| Author | Merad, Miriam Sathe, Priyanka Julie, Helft Miller, Jennifer Arthur, Mortha |
| Copyright Year | 2013 |
| Abstract | Dendritic cells (DCs) form a remarkable cellular network that shapes adaptive immune responses according to peripheral cues. After four decades of research, we now know that DCs arise from a hematopoietic lineage distinct from other leukocytes, establishing the DC system as a unique hematopoietic branch. Recent work has also established that tissue DCs consist of developmentally and functionally distinct subsets that differentially regulate T lymphocyte function. This review discusses major advances in our understanding of the regulation of DC lineage commitment, differentiation, diversification, and function in situ. |
| Related Links | http://dx.doi.org/10.1146/annurev-immunol-020711-074950 |
| File Format | |
| ISSN | 07320582 |
| e-ISSN | 15453278 |
| Journal | Annual review of immunology |
| Volume Number | 31 |
| Language | English |
| Publisher Date | 2013-03-21 |
| Access Restriction | Open |
| Subject Keyword | Immunology Immunology and Allergy Research in Higher Education |
| Content Type | Text |
| Resource Type | Article |
| Subject | Immunology and Allergy Immunology |