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Small nucleolar RNAs in cancer
| Content Provider | PubMed Central |
|---|---|
| Author | Mannoor, Kaiissar Liao, Jipei Jiang, Feng |
| Abstract | Non-coding RNAs (ncRNAs) are important regulatory molecules involving in various physiological cellular processes. Alterations of ncRNAs, particularly microRNAs, play crucial roles in tumorigenesis. Accumulating evidence indicates that small nucleolar RNAs (snoRNAs), another large class of ncRNAs, are gaining prominence and more actively involved in carcinogenesis than previously thought. Some snoRNAs exhibit differential expression patterns in a variety of human cancers and demonstrate capability to affect cell transformation, tumorigenesis, and metastasis. We are beginning to comprehend the functional repercussions of snoRNAs in the development and progression of malignancy. In this review, we will describe current studies that have shed new light on the functions of snoRNAs in carcinogenesis and the potential applications for cancer diagnosis and diagnosis. |
| Related Links | http://dx.doi.org/10.1016/j.bbcan.2012.03.005 |
| File Format | |
| ISSN | 0304419X |
| Journal | Biochimica et biophysica acta |
| Issue Number | 1 |
| Volume Number | 1826 |
| Language | English |
| Publisher Date | 2012-08-01 |
| Access Restriction | Open |
| Subject Keyword | Genetics Cancer Research Oncology Research in Higher Education |
| Content Type | Text |
| Resource Type | Article |
| Subject | Genetics Cancer Research Oncology |
