NDLI: Drosophila Cancer Models

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Drosophila Cancer Models

Content Provider	PubMed Central
Author	Rudrapatna, Vivek A. Cagan, Ross L. Das, Tirtha K.
Copyright Year	2011
Abstract	Cancer is driven by complex genetic and cellular mechanisms. Recently, the Drosophila community has become increasingly interested in exploring cancer issues. The Drosophila field has made seminal contributions to many of the mechanisms that are fundamental to the cancer process; several of these mechanisms have already been validated in vertebrates. Less well known are the Drosophila field's early direct contributions to the cancer field: some of the earliest tumor suppressors were identified in flies. In this review, we identify major contributions that Drosophila studies have made toward dissecting the pathways and mechanisms underlying tumor progression. We also highlight areas, such as drug discovery, where we expect Drosophila studies to make a major scientific impact in the future.
Related Links	http://dx.doi.org/10.1002/dvdy.22771
Ending Page	118
Page Count	12
Starting Page	107
File Format	PDF
ISSN	10970177
e-ISSN	10970177
Journal	Developmental dynamics : an official publication of the American Association of Anatomists
Issue Number	1
Volume Number	241
Language	English
Publisher Date	2012-01-01
Access Restriction	Open
Subject Keyword	Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Developmental Biology

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