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| Content Provider | PubMed Central |
|---|---|
| Author | Lu, Ying-ying Zhu, Feng Jing, Da-dao Wu, Xie-ning Lu, Lun-gen Zhou, Gen-quan Wang, Xing-peng |
| Copyright Year | 2013 |
| Abstract | Multiple endocrine neoplasia type 1 (MEN1) is a rare hereditary syndrome known to predispose subjects to endocrine neoplasms in a variety of tissues such as the parathyroid glands, pituitary gland, pancreas and gastrointestinal tract. We herein report a patient with a past history of pituitary adenoma, presenting with symptoms of chronic diarrhea for nearly one year and a sudden upper gastrointestinal hemorrhage as well as perforation without signs. Nodules in the duodenum and in the uncinate process and tail of pancreas and enlargement of the parathyroid glands were detected on preoperative imaging. Gastroscopy revealed significant ulceration and esophageal reflux diseases. The patient underwent subtotal parathyroidectomy and autotransplantation, pylorus-preserving pancreaticoduodenectomy and pancreatic tail resection and recovered well. The results observed in our patient suggest that perforation and bleeding of intestine might be symptoms of Zollinger-Ellison Syndrome in patients with MEN1. |
| Related Links | http://dx.doi.org/10.3748/wjg.v19.i8.1322 |
| Starting Page | 1322 |
| File Format | |
| ISSN | 10079327 |
| Journal | World Journal of Gastroenterology : WJG |
| Issue Number | 8 |
| Volume Number | 19 |
| Language | English |
| Publisher | Baishideng Publishing Group Co., Limited |
| Publisher Date | 2013-01-01 |
| Access Restriction | Open |
| Rights Holder | Baishideng Publishing Group Co., Limited |
| Subject Keyword | Gastroenterology Research in Higher Education |
| Content Type | Text |
| Resource Type | Article |
| Subject | Gastroenterology |
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