NDLI: Malakoplakia of the esophagus caused by human papillomavirus infection

Content Provider	PubMed Central
Author	Yang, Ya-li Xie, Yu-cheng Li, Xiao-ling Guo, Jing Sun, Tao Tang, Jing
Copyright Year	2012
Abstract	Malakoplakia is a rare granulomatous disease probably caused by infection and characterized histologically by Michaelis-Gutmann bodies. We report a more rarely seen case esophageal malakoplakia in a 54-year-old woman. She presented with coughing while eating and drinking. Gastroscopy showed yellow nodules in the esophagus, and endoscopic ultrasonography showed a space-occupying lesion in the substratum of the esophageal mucosa. All findings highly resembled esophageal cancer. Histopathological examination finally indentified this space-occupying lesion as malakoplakia and not cancer. Immunohistochemistry showed that she had human papillomavirus (HPV) infection in the esophagus, which indicates that infection was responsible for the malakoplakia. This is believed to be the first case of malakoplakia in the esophagus, and more importantly, we established that HPV infection was the initiator of esophageal malakoplakia.
Related Links	http://dx.doi.org/10.3748/wjg.v18.i45.6690
Starting Page	6690
File Format	PDF
ISSN	10079327
Journal	World Journal of Gastroenterology : WJG
Issue Number	45
Volume Number	18
Language	English
Publisher	Baishideng Publishing Group Co., Limited
Publisher Date	2012-12-07
Access Restriction	Open
Rights Holder	Baishideng Publishing Group Co., Limited
Subject Keyword	Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Gastroenterology

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Malakoplakia of the esophagus caused by human papillomavirus infection