NDLI: Determining the Effects of Electrical Stimulation on Functional Recovery of Denervated Rat Gastrocnemius Muscle using Motor Unit Number Estimation

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Determining the Effects of Electrical Stimulation on Functional Recovery of Denervated Rat Gastrocnemius Muscle using Motor Unit Number Estimation

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Determining the Effects of Electrical Stimulation on Functional Recovery of Denervated Rat Gastrocnemius Muscle using Motor Unit Number Estimation

Content Provider	PubMed Central
Author	Willand, Michael P. Holmes, Michael Bain, James R. Fahnestock, Margaret Bruin, Hubert De
Copyright Year	2011
Abstract	The use of electrical muscle stimulation to treat denervated muscle prior to delayed reinnervation has been widely debated. There is evidence showing both positive and negative results following different protocols of electrical stimulation. In this study we investigated the role electrical stimulation has on muscle reinnervation following immediate and delayed nerve repair using motor unit estimation techniques. Rat gastrocnemius muscle was denervated and repaired using the peroneal nerve either immediately or following three-months with and without electrical stimulation. Motor unit counts, average motor unit sizes, and maximum compound action potentials were measured three-months following peroneal nerve repair. Motor unit counts in animals that were denervated and stimulated were significantly higher than those that were denervated and not stimulated. Both average motor unit sizes and maximum compound action potentials showed no significant differences between denervated and denervated-stimulated animals. These results provide evidence that electrical stimulation prior to delayed nerve repair increases muscle receptivity to regenerating axons and may be a worthwhile treatment for peripheral nerve injuries.
Related Links	http://dx.doi.org/10.1109/iembs.2011.6090557
Starting Page	1977
File Format	PDF
ISSN	1557170X
Journal	Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference
Volume Number	2011
Language	English
Publisher Date	2011-08-01
Access Restriction	Open
Subject Keyword	Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

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