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| Content Provider | PubMed Central |
|---|---|
| Author | Onur, Mudanyali Dimitrov, Stoyan Sikora, Uzair Padmanabhan, Swati Isa, Navruz Ozcan, Aydogan |
| Abstract | We demonstrate a cellphone based Rapid-Diagnostic-Test (RDT) reader platform that can work with various lateral flow immuno-chromatographic assays and similar tests to sense the presence of a target analyte in a sample. This compact and cost-effective digital RDT reader, weighing only ~65 grams, mechanically attaches to the existing camera unit of a cellphone, where various types of RDTs can be inserted to be imaged in reflection or transmission modes under light-emitting-diode (LED) based illumination. Captured raw images of these tests are then digitally processed (within less than 0.2 sec/image) through a smart application running on the cellphone for validation of the RDT as well as for automated reading of its diagnostic result. The same smart application running on the cellphone then transmits the resulting data, together with the RDT images and other related information (e.g., demographic data) to a central server, which presents the diagnostic results on a world-map through geo-tagging. This dynamic spatio-temporal map of various RDT results can then be viewed and shared using internet browsers or through the same cellphone application. We tested this platform using malaria, tuberculosis (TB) as well as HIV RDTs by installing it on both Android based smart-phones as well as an iPhone. Providing real-time spatio-temporal statistics for the prevalence of various infectious diseases, this smart RDT reader platform running on cellphones might assist health-care professionals and policy makers to track emerging epidemics worldwide and help epidemic preparedness. |
| Related Links | http://dx.doi.org/10.1039/c2lc40235a |
| Starting Page | 2678 |
| File Format | |
| ISSN | 14730197 |
| e-ISSN | 14730189 |
| Journal | Lab on a Chip |
| Issue Number | 15 |
| Volume Number | 12 |
| Language | English |
| Publisher Date | 2012-01-01 |
| Access Restriction | Open |
| Subject Keyword | Biochemistry Bioengineering Chemistry(all) Biomedical Engineering Research in Higher Education |
| Content Type | Text |
| Resource Type | Article |
| Subject | Chemistry Nanoscience and Nanotechnology Biochemistry Bioengineering Biomedical Engineering |
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