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| Content Provider | PubMed Central |
|---|---|
| Author | Lee, Bong Eun Kim, Gwang Ha |
| Copyright Year | 2012 |
| Abstract | Globus is a persistent or intermittent non-painful sensation of a lump or foreign body in the throat. It is a commonly encountered clinical condition that is usually long-lasting, difficult to treat, and has a tendency to recur. Furthermore, due to the uncertain etiology of globus, it remains difficult to establish standard investigation and treatment strategies for affected patients. As a first step for managing globus, careful history taking and nasolaryngoscopy are essential. Given the benign nature of the condition and the recent notion that gastroesophageal reflux disease is a major cause of globus, empirical therapy with a high dose of proton pump inhibitors is reasonable for patients with typical globus. If patients are nonresponsive to this therapy, definitive assessments such as endoscopy, multichannel intraluminal impedance/pH monitoring, and manometry should be considered. Speech and language therapy, anti-depressants, and cognitive-behavioral therapy can be helpful in patients whose symptoms persist despite negative investigations. |
| Related Links | http://dx.doi.org/10.3748/wjg.v18.i20.2462 |
| Starting Page | 2462 |
| File Format | |
| ISSN | 10079327 |
| Journal | World Journal of Gastroenterology : WJG |
| Issue Number | 20 |
| Volume Number | 18 |
| Language | English |
| Publisher | Baishideng Publishing Group Co., Limited |
| Publisher Date | 2012-01-01 |
| Access Restriction | Open |
| Rights Holder | Baishideng Publishing Group Co., Limited |
| Subject Keyword | Gastroenterology Research in Higher Education |
| Content Type | Text |
| Resource Type | Article |
| Subject | Gastroenterology |
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