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| Content Provider | PubMed Central |
|---|---|
| Author | Kim, Daniel Dyvorne, Hadrien A. Otazo, Ricardo Feng, Li Sodickson, Daniel K. Lee, Vivian S. |
| Copyright Year | 2011 |
| Abstract | Phase-contrast (PC) cine MRI is a promising method for assessment of pathologic hemodynamics, including cardiovascular and hepatoportal vascular dynamics, but its low data acquisition efficiency limits the achievable spatial and temporal resolutions within clinically acceptable breath-hold durations. We propose to accelerate PC cine MRI using an approach which combines compressed sensing and parallel imaging (k-t SPARSE-SENSE). We validated the proposed 6-fold accelerated PC cine MRI against 3-fold accelerated PC cine MRI with parallel imaging (generalized autocalibrating partially parallel acquisitions). With the programmable flow pump, we simulated a time varying waveform emulating hepatic blood flow. Normalized root mean square error between two sets of velocity measurements was 2.59%. In multiple blood vessels of 12 control subjects, two sets of mean velocity measurements were in good agreement (mean difference = –0.29 cm/s; lower and upper 95% limits of agreement = –5.26 and 4.67 cm/s, respectively). The mean phase noise, defined as the standard deviation of the phase in a homogeneous stationary region, was significantly lower for k-t SPARSE-SENSE than for generalized autocalibrating partially parallel acquisitions (0.05 ± 0.01 vs. 0.19 ± 0.06 radians, respectively; P < 0.01). The proposed 6-fold accelerated PC cine MRI pulse sequence with k-t SPARSE-SENSE is a promising investigational method for rapid velocity measurement with relatively high spatial (1.7 mm × 1.7 mm) and temporal (~35 ms) resolutions. |
| Related Links | http://dx.doi.org/10.1002/mrm.23088 |
| Starting Page | 1054 |
| File Format | |
| ISSN | 15222594 |
| e-ISSN | 15222594 |
| Journal | Magnetic Resonance in Medicine |
| Issue Number | 4 |
| Volume Number | 67 |
| Language | English |
| Publisher Date | 2012-04-01 |
| Access Restriction | Open |
| Subject Keyword | Research in Higher Education |
| Content Type | Text |
| Resource Type | Article |
| Subject | Radiology, Nuclear Medicine and Imaging |
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