NDLI: Working memory, long-term memory, and medial temporal lobe function

Please wait, while we are loading the content...

Working memory, long-term memory, and medial temporal lobe function

Content Provider	PubMed Central
Author	Annette, Jeneson Squire, Larry R.
Abstract	Early studies of memory-impaired patients with medial temporal lobe (MTL) damage led to the view that the hippocampus and related MTL structures are involved in the formation of long-term memory and that immediate memory and working memory are independent of these structures. This traditional idea has recently been revisited. Impaired performance in patients with MTL lesions on tasks with short retention intervals, or no retention interval, and neuroimaging findings with similar tasks have been interpreted to mean that the MTL is sometimes needed for working memory and possibly even for visual perception itself. We present a reappraisal of this interpretation. Our main conclusion is that, if the material to be learned exceeds working memory capacity, if the material is difficult to rehearse, or if attention is diverted, performance depends on long-term memory even when the retention interval is brief. This fundamental notion is better captured by the terms subspan memory and supraspan memory than by the terms short-term memory and long-term memory. We propose methods for determining when performance on short-delay tasks must depend on long-term (supraspan) memory and suggest that MTL lesions impair performance only when immediate memory and working memory are insufficient to support performance. In neuroimaging studies, MTL activity during encoding is influenced by the memory load and correlates positively with long-term retention of the material that was presented. The most parsimonious and consistent interpretation of all the data is that subspan memoranda are supported by immediate memory and working memory and are independent of the MTL.
Related Links	http://dx.doi.org/10.1101/lm.024018.111
Ending Page	25
Page Count	11
Starting Page	15
File Format	PDF
ISSN	10720502
e-ISSN	15495485
Journal	Learning & Memory
Issue Number	1
Volume Number	19
Language	English
Publisher	Cold Spring Harbor Laboratory Press
Publisher Date	2011-12-16
Access Restriction	Open
Rights Holder	Cold Spring Harbor Laboratory Press
Subject Keyword	Cognitive Neuroscience Cellular and Molecular Neuroscience Neuropsychology and Physiological Psychology Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Cognitive Neuroscience Neuropsychology and Physiological Psychology Cellular and Molecular Neuroscience

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Impaired Auditory Recognition Memory in Amnesic Patients with Medial Temporal Lobe Lesions

Distinct roles for medial temporal lobe structures in memory for objects and their locations

Retrograde amnesia in patients with hippocampal, medial temporal, temporal lobe, or frontal pathology

Overcoming interference: An fMRI investigation of pattern separation in the medial temporal lobe

Dissociable contributions within the medial temporal lobe to encoding of object-location associations

The medial temporal lobe and the attributes of memory

Lack of evidence for a role of medial temporal lobe structures in visual perception

Working Memory for Temporal and Nontemporal Events in Monkeys

Electrolytic lesions of the medial prefrontal cortex do not interfere with long-term memory of extinction of conditioned fear

Working memory, long-term memory, and medial temporal lobe function

Similar Documents

Impaired Auditory Recognition Memory in Amnesic Patients with Medial Temporal Lobe Lesions

Distinct roles for medial temporal lobe structures in memory for objects and their locations

Retrograde amnesia in patients with hippocampal, medial temporal, temporal lobe, or frontal pathology

Overcoming interference: An fMRI investigation of pattern separation in the medial temporal lobe

Dissociable contributions within the medial temporal lobe to encoding of object-location associations

The medial temporal lobe and the attributes of memory

Lack of evidence for a role of medial temporal lobe structures in visual perception

Working Memory for Temporal and Nontemporal Events in Monkeys

Electrolytic lesions of the medial prefrontal cortex do not interfere with long-term memory of extinction of conditioned fear

Working memory, long-term memory, and medial temporal lobe function