NDLI: Adrenal Ganglioneuroma with Multifocal Retroperitoneal Extension: A Challenging Diagnosis

Content Provider	PubMed Central
Author	Marco, Oderda Cattaneo, Elena Soria, Francesco Barreca, Antonella Luigi, Chiusa Morelli, Bruno Andrea, Zitella Paolo, Gontero
Editor	Atala, Anthony
Copyright Year	2011
Abstract	A ganglioneuroma (GN) is the rarest and most benign of the neuroblastic tumors and originates from neural crest cells wherever sympathetic nervous tissue exists, such as in the retroperitoneum and adrenal gland. The diagnosis can be very challenging, given the rarity and asymptomatic presentation of this neoplasia, and can be achieved only by means of histological evaluation. Although benign, a few cases of metastatic GNs have been reported in the literature. The prognosis, however, seems to be excellent after surgical resection. We describe a rare case of multifocal retroperitoneal GN, diagnosed incidentally in a 46-year-old woman, with para-aortic and adrenal localizations. After intraoperative pathological diagnosis was made, complete excision of all the visible masses was performed. The postoperative period was uneventful and she was recurrence free 3 months after surgery. To our knowledge, this is the first case report of a multifocal retroperitoneal GN. Among the broad differential diagnoses of adrenal incidentalomas, an adrenal location of neuroblastic tumors should not be forgotten.
Related Links	http://dx.doi.org/10.1100/tsw.2011.144
Ending Page	1553
Page Count	6
Starting Page	1548
File Format	PDF
ISSN	1537744X
e-ISSN	1537744X
Journal	TheScientificWorldJournal
Volume Number	11
Language	English
Publisher	TheScientificWorldJOURNAL
Publisher Date	2011-01-01
Access Restriction	Open
Rights Holder	TheScientificWorldJOURNAL
Subject Keyword	Biochemistry, Genetics and Molecular Biology(all) Environmental Science(all) Medicine(all) Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Medicine Biochemistry, Genetics and Molecular Biology Environmental Science

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