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Enteropathy associated T cell lymphoma: common in coeliac disease
| Content Provider | PubMed Central |
|---|---|
| Author | Colleran, Gabrielle Christina Cronin, Kevin Christopher Casey, Mary Bennani, Fadel Tobbia, Iqdam Barry, Kevin |
| Abstract | A 56-year-old male admitted with haematemesis and epigastric pain and severe weight loss on a background of coeliac disease. Computed tomography (CT) abdomen revealed a thickening of the mucosal folds of a short segment of jejunum. He deteriorated and had an exploratory laparotomy and bowel resection with side-side jejojejunal stapled anastomosis and extended right hemicolectomy and ileocolic anastomosis. Histology demonstrated multifocal high-grade malignant T cell lymphoma. Coeliac disease is a very common lifelong disorder. It is associated with osteoporosis, infertility, autoimmune disorders and increased risk of malignancy including an increased risk of non-Hodgkin’s lymphoma (NHL) especially of the T cell type. Enteropathy-type T cell lymphoma is associated with a very poor prognosis. There is significant evidence that adherence to a gluten-free diet decreases the risk of developing enteropathy-type T cell lymphoma and helps to prevent development of autoimmune diseases, diabetes mellitus and osteoporosis in patients with coeliac disease. |
| Related Links | http://dx.doi.org/10.1136/bcr.06.2008.0270 |
| File Format | |
| ISSN | 1757790X |
| e-ISSN | 1757790X |
| Journal | BMJ Case Reports |
| Volume Number | 2009 |
| Language | English |
| Publisher | BMJ Publishing Group |
| Publisher Date | 2009-02-22 |
| Access Restriction | Open |
| Rights Holder | BMJ Publishing Group |
| Subject Keyword | Research in Higher Education |
| Content Type | Text |
| Resource Type | Article |
| Subject | Medicine |