NDLI: Long-Term Daclizumab Therapy in Relapsing

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Long-Term Daclizumab Therapy in Relapsing—Remitting Multiple Sclerosis

Content Provider	PubMed Central
Author	Rojas, Monica A. Carlson, Noel G. Miller, Thomas L. Rose, John W.
Copyright Year	2009
Abstract	We performed a retrospective review of side effects and clinical outcomes in relapsing—remitting (RR) multiple sclerosis (MS) patients receiving long-term treatment with daclizumab. Twelve patients with RR MS were initially treated with daclizumab at 1 mg/kg IV, again 14 days later and then monthly treatments (average duration 42.1 months). Daclizumab dose (0.85 mg/kg to 1.5 mg/kg) was adjusted based on clinical response. Daclizumab was generally well tolerated. There was a significant reduction in relapse rate and improvement in Expanded Disability Status Scores (EDSSs) (p < 0.0001). Long-term treatment with daclizumab in RR MS patients has apparent benefit that will require formal confirmation.
Related Links	http://dx.doi.org/10.1177/1756285609337992
Ending Page	297
Page Count	7
Starting Page	291
File Format	PDF
ISSN	17562856
e-ISSN	17562864
Journal	Therapeutic Advances in Neurological Disorders
Issue Number	5
Volume Number	2
Language	English
Publisher	SAGE Publications
Publisher Date	2009-09-01
Access Restriction	Open
Rights Holder	SAGE Publications
Subject Keyword	Pharmacology Neurology Clinical Neurology Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Neurology Neurology (clinical) Pharmacology

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