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Prediction of function in protein superfamilies
| Content Provider | PubMed Central |
|---|---|
| Author | Copley, Shelley D. |
| Copyright Year | 2009 |
| Abstract | Assignment of function for enzymes encoded in sequenced genomes is a challenging task. Predictions of enzyme function can be made using clues from superfamily assignment, structure, genome context, phylogenetic conservation, and virtual screening to identify potential ligands. Ultimately, confident assignment of function requires experimental verification as well as an understanding of the physiological role of an enzyme in the context of the metabolic network. |
| Related Links | http://dx.doi.org/10.3410/B1-91 |
| Starting Page | 91 |
| File Format | |
| ISSN | 1757594X |
| e-ISSN | 1757594X |
| Journal | F1000 Biology Reports |
| Volume Number | 1 |
| Language | English |
| Publisher | Biology Reports |
| Access Restriction | Open |
| Rights Holder | Biology Reports |
| Subject Keyword | Research in Higher Education |
| Content Type | Text |
| Resource Type | Article |
| Subject | Neuroscience Immunology and Microbiology Biochemistry, Genetics and Molecular Biology Pharmacology, Toxicology and Pharmaceutics |